Targeting Lysosomal Dysfunction and Oxidative Stress in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of vision loss in the Western world, and it currently lacks effective therapy. It is believed that AMD initiates in the aged retinal pigment epithelium (RPE), which presents lysosomal dysfunction and oxidative stress (OxS) that ultimately l...

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Bibliographic Details
Main Authors: Ana S. Falcão, Margarida L. Pedro, Sandra Tenreiro, Miguel C. Seabra
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antioxidants
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Online Access:https://www.mdpi.com/2076-3921/14/5/596
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