Refining α-synuclein seed amplification assays to distinguish Parkinson’s disease from multiple system atrophy
Abstract Background Parkinson’s disease (PD) and multiple system atrophy (MSA) are two distinct α-synucleinopathies traditionally differentiated through clinical symptoms. Early diagnosis of MSA is problematic, and seed amplification assays (SAAs), such as real-time quaking-induced conversion (RT-Qu...
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Main Authors: | James A. Wiseman, Clinton P. Turner, Richard L. M. Faull, Glenda M. Halliday, Birger Victor Dieriks |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Translational Neurodegeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40035-025-00469-6 |
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