Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE)
We present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptom...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2017/2890436 |
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| author | Gareth Garrett Nicola Ambrose Zaib Davids Dorothea Bindman |
| author_facet | Gareth Garrett Nicola Ambrose Zaib Davids Dorothea Bindman |
| author_sort | Gareth Garrett |
| collection | DOAJ |
| description | We present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptoms. The most recent flare occurred when she was aged seventeen. She had cutaneous symptoms which coincided with an episode of hypomania. Her mental state further deteriorated following steroid treatment. She exhibited affective and psychotic symptoms. Treatment with cyclophosphamide and olanzapine was associated with an improvement in both cutaneous and neuropsychiatric symptoms. Previously aged sixteen the patient had presented with cutaneous symptoms and a moderate depressive episode which was also exacerbated by steroid treatment. The patient’s mood improved when the dose of oral steroids was reduced to a daily dose of 15–20 mg prednisolone. |
| format | Article |
| id | doaj-art-2a88873297fd40abb0e26cce0a1cbf9d |
| institution | Kabale University |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-2a88873297fd40abb0e26cce0a1cbf9d2025-02-03T07:25:17ZengWileyCase Reports in Psychiatry2090-682X2090-68382017-01-01201710.1155/2017/28904362890436Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE)Gareth Garrett0Nicola Ambrose1Zaib Davids2Dorothea Bindman3University College London Hospitals NHS Trust, London, UKUniversity College London Hospitals NHS Trust, London, UKUniversity College London Hospitals NHS Trust, London, UKUniversity College London Hospitals NHS Trust, London, UKWe present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptoms. The most recent flare occurred when she was aged seventeen. She had cutaneous symptoms which coincided with an episode of hypomania. Her mental state further deteriorated following steroid treatment. She exhibited affective and psychotic symptoms. Treatment with cyclophosphamide and olanzapine was associated with an improvement in both cutaneous and neuropsychiatric symptoms. Previously aged sixteen the patient had presented with cutaneous symptoms and a moderate depressive episode which was also exacerbated by steroid treatment. The patient’s mood improved when the dose of oral steroids was reduced to a daily dose of 15–20 mg prednisolone.http://dx.doi.org/10.1155/2017/2890436 |
| spellingShingle | Gareth Garrett Nicola Ambrose Zaib Davids Dorothea Bindman Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE) Case Reports in Psychiatry |
| title | Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE) |
| title_full | Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE) |
| title_fullStr | Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE) |
| title_full_unstemmed | Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE) |
| title_short | Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE) |
| title_sort | course of neuropsychiatric symptoms during flares of systemic lupus erythematosus sle |
| url | http://dx.doi.org/10.1155/2017/2890436 |
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