Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse

Objective. To investigate the biomechanical characteristics of the cornea in patients with mitral valve prolapse (MVP) and the prevalence of keratoconus (KC) in MVP. Materials and Methods. Fifty-two patients with MVP, 39 patients with KC, and 45 control individuals were recruited in this study. All...

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Main Authors: Emine Kalkan Akcay, Murat Akcay, Betul Seher Uysal, Pinar Kosekahya, Abdullah Nabi Aslan, Mehtap Caglayan, Cemal Koseoglu, Fatma Yulek, Nurullah Cagil
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2014/402193
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author Emine Kalkan Akcay
Murat Akcay
Betul Seher Uysal
Pinar Kosekahya
Abdullah Nabi Aslan
Mehtap Caglayan
Cemal Koseoglu
Fatma Yulek
Nurullah Cagil
author_facet Emine Kalkan Akcay
Murat Akcay
Betul Seher Uysal
Pinar Kosekahya
Abdullah Nabi Aslan
Mehtap Caglayan
Cemal Koseoglu
Fatma Yulek
Nurullah Cagil
author_sort Emine Kalkan Akcay
collection DOAJ
description Objective. To investigate the biomechanical characteristics of the cornea in patients with mitral valve prolapse (MVP) and the prevalence of keratoconus (KC) in MVP. Materials and Methods. Fifty-two patients with MVP, 39 patients with KC, and 45 control individuals were recruited in this study. All the participants underwent ophthalmologic examination, corneal analysis with the Sirius system (CSO), and the corneal biomechanical evaluation with Reichert ocular response analyzer (ORA). Results. KC was found in six eyes of four patients (5.7%) and suspect KC in eight eyes of five patients (7.7%) in the MVP group. KC was found in one eye of one patient (1.1%) in the control group (P=0.035). A significant difference occurred in the mean CH and CRF between the MVP and control groups (P=0.006 and P=0.009, resp.). All corneal biomechanical and topographical parameters except IOPcc were significantly different between the KC-MVP groups (P<0.05). Conclusions. KC prevalence is higher than control individuals in MVP patients and the biomechanical properties of the cornea are altered in patients with MVP. These findings should be considered when the MVP patients are evaluated before refractive surgery.
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institution Kabale University
issn 2090-004X
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spelling doaj-art-2a881a36b3d3405299045f8f4cb729c42025-02-03T07:25:43ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/402193402193Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve ProlapseEmine Kalkan Akcay0Murat Akcay1Betul Seher Uysal2Pinar Kosekahya3Abdullah Nabi Aslan4Mehtap Caglayan5Cemal Koseoglu6Fatma Yulek7Nurullah Cagil8Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, TurkeyObjective. To investigate the biomechanical characteristics of the cornea in patients with mitral valve prolapse (MVP) and the prevalence of keratoconus (KC) in MVP. Materials and Methods. Fifty-two patients with MVP, 39 patients with KC, and 45 control individuals were recruited in this study. All the participants underwent ophthalmologic examination, corneal analysis with the Sirius system (CSO), and the corneal biomechanical evaluation with Reichert ocular response analyzer (ORA). Results. KC was found in six eyes of four patients (5.7%) and suspect KC in eight eyes of five patients (7.7%) in the MVP group. KC was found in one eye of one patient (1.1%) in the control group (P=0.035). A significant difference occurred in the mean CH and CRF between the MVP and control groups (P=0.006 and P=0.009, resp.). All corneal biomechanical and topographical parameters except IOPcc were significantly different between the KC-MVP groups (P<0.05). Conclusions. KC prevalence is higher than control individuals in MVP patients and the biomechanical properties of the cornea are altered in patients with MVP. These findings should be considered when the MVP patients are evaluated before refractive surgery.http://dx.doi.org/10.1155/2014/402193
spellingShingle Emine Kalkan Akcay
Murat Akcay
Betul Seher Uysal
Pinar Kosekahya
Abdullah Nabi Aslan
Mehtap Caglayan
Cemal Koseoglu
Fatma Yulek
Nurullah Cagil
Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse
Journal of Ophthalmology
title Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse
title_full Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse
title_fullStr Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse
title_full_unstemmed Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse
title_short Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse
title_sort impaired corneal biomechanical properties and the prevalence of keratoconus in mitral valve prolapse
url http://dx.doi.org/10.1155/2014/402193
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