Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer

Background: A variety of molecular markers have been evaluated for the development of a non-invasive approach to the diagnosis of colorectal cancer. We aimed to validate the diagnostic accuracy, using the same threshold as in the previous pilot study, of fluorescent long DNA test as a relatively sim...

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Main Authors: Daniele Calistri, Claudia Rengucci, Chiara Molinari, Enrico Ricci, Elena Cavargini, Emanuela Scarpi, Gian Luigi Milandri, Carla Fabbri, Alberto Ravaioli, Antonio Russo, Dino Amadori, Rosella Silvestrini
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0443
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author Daniele Calistri
Claudia Rengucci
Chiara Molinari
Enrico Ricci
Elena Cavargini
Emanuela Scarpi
Gian Luigi Milandri
Carla Fabbri
Alberto Ravaioli
Antonio Russo
Dino Amadori
Rosella Silvestrini
author_facet Daniele Calistri
Claudia Rengucci
Chiara Molinari
Enrico Ricci
Elena Cavargini
Emanuela Scarpi
Gian Luigi Milandri
Carla Fabbri
Alberto Ravaioli
Antonio Russo
Dino Amadori
Rosella Silvestrini
author_sort Daniele Calistri
collection DOAJ
description Background: A variety of molecular markers have been evaluated for the development of a non-invasive approach to the diagnosis of colorectal cancer. We aimed to validate the diagnostic accuracy, using the same threshold as in the previous pilot study, of fluorescent long DNA test as a relatively simple and inexpensive tool for colorectal cancer detection.
format Article
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institution Kabale University
issn 1570-5870
1875-8606
language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series Cellular Oncology
spelling doaj-art-2a7ad0baf324484697d3986b5b98a6a02025-02-03T05:58:12ZengWileyCellular Oncology1570-58701875-86062009-01-01311111710.3233/CLO-2009-0443Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal CancerDaniele Calistri0Claudia Rengucci1Chiara Molinari2Enrico Ricci3Elena Cavargini4Emanuela Scarpi5Gian Luigi Milandri6Carla Fabbri7Alberto Ravaioli8Antonio Russo9Dino Amadori10Rosella Silvestrini11Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, ItalyIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, ItalyIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, ItalyDepartment of Gastroenterology, Morgagni-Pierantoni Hospital, Forlì, ItalyDepartment of Gastroenterology, Morgagni-Pierantoni Hospital, Forlì, ItalyIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, ItalyDepartment of Gastroenterology, Bufalini Hospital, Cesena, ItalyDepartment of Oncology, Infermi Hospital, Rimini, ItalyDepartment of Oncology, Infermi Hospital, Rimini, ItalyDepartment of Surgery and Oncology, University of Palermo, Palermo, ItalyIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, ItalyIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, ItalyBackground: A variety of molecular markers have been evaluated for the development of a non-invasive approach to the diagnosis of colorectal cancer. We aimed to validate the diagnostic accuracy, using the same threshold as in the previous pilot study, of fluorescent long DNA test as a relatively simple and inexpensive tool for colorectal cancer detection.http://dx.doi.org/10.3233/CLO-2009-0443
spellingShingle Daniele Calistri
Claudia Rengucci
Chiara Molinari
Enrico Ricci
Elena Cavargini
Emanuela Scarpi
Gian Luigi Milandri
Carla Fabbri
Alberto Ravaioli
Antonio Russo
Dino Amadori
Rosella Silvestrini
Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer
Cellular Oncology
title Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer
title_full Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer
title_fullStr Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer
title_full_unstemmed Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer
title_short Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer
title_sort quantitative fluorescence determination of long fragment dna in stool as a marker for the early detection of colorectal cancer
url http://dx.doi.org/10.3233/CLO-2009-0443
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