Integrated analysis of M2 macrophage-related gene prognostic model and single-cell sequence to predict immunotherapy response in lung adenocarcinoma

Integrated analysis of M2 macrophage-related gene prognostic model and single-cell sequence to predict immunotherapy response in lung adenocarcinoma

BackgroundLung adenocarcinoma (LUAD) patients have high heterogeneity. The significance and clinical value of M2 macrophage-related genes in LUAD require further exploration. We aimed to construct a prognostic signature to predict the immunotherapy efficacy and prognosis in LUAD.MethodsGSE26939 and...

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Bibliographic Details
Main Authors: Meifang Li, Zhiping Wang, Bin Huang, Yanyun Lai, Meng Zhang, Cheng Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Genetics
Subjects:
lung adenocarcinoma
tumor microenvironment
macrophages
prognosis
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1519677/full
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