Application of the age-period-cohort model in tuberculosis

Up to now, tuberculosis (TB) remains a global public health problem, posing a serious threat to human health. Traditional methods for analyzing time-varying trends, such as age and period, tend to ignore the poor impact of birth cohorts, which is an important factor in the development of TB. The age...

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Main Authors: Dan Luo, Fengying Wang, Songhua Chen, Yu Zhang, Wei Wang, Qian Wu, Yuxiao Ling, Yiqing Zhou, Yang Li, Kui Liu, Bin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1486946/full
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author Dan Luo
Fengying Wang
Songhua Chen
Yu Zhang
Wei Wang
Qian Wu
Yuxiao Ling
Yiqing Zhou
Yang Li
Kui Liu
Bin Chen
author_facet Dan Luo
Fengying Wang
Songhua Chen
Yu Zhang
Wei Wang
Qian Wu
Yuxiao Ling
Yiqing Zhou
Yang Li
Kui Liu
Bin Chen
author_sort Dan Luo
collection DOAJ
description Up to now, tuberculosis (TB) remains a global public health problem, posing a serious threat to human health. Traditional methods for analyzing time-varying trends, such as age and period, tend to ignore the poor impact of birth cohorts, which is an important factor in the development of TB. The age-period-cohort (APC) model, a statistical method widely used in recent decades in economics, sociology, and epidemiology, can quantitatively estimate the efficacy of different age, period, and birth cohort groups for TB by separating the effects of these three dimensions and controlling for confounding factors among the time variables. The purpose of this paper is to briefly review the model, focus on the application of the existing APC model in the field of TB, and explain its advantages and disadvantages. This study will help to provides a theoretical basis and reference for using the APC model in TB analysis and prediction.
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institution Kabale University
issn 2296-2565
language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Public Health
spelling doaj-art-2a2069c4ad6748f9aa9c9c5afb060a252025-01-29T06:46:15ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011310.3389/fpubh.2025.14869461486946Application of the age-period-cohort model in tuberculosisDan Luo0Fengying Wang1Songhua Chen2Yu Zhang3Wei Wang4Qian Wu5Yuxiao Ling6Yiqing Zhou7Yang Li8Kui Liu9Bin Chen10School of Public Health, Hangzhou Medical College, Hangzhou, ChinaDepartment of Tuberculosis and AIDS Control and Prevention, Jinhua Municipal Center for Disease Control and Prevention, Jinhua, ChinaDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, ChinaDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, ChinaDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, ChinaDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, ChinaSchool of Public Health, Health Science Center, Ningbo University, Ningbo, ChinaSchool of Public Health, Hangzhou Medical College, Hangzhou, ChinaSchool of Public Health, Hangzhou Normal University, Hangzhou, ChinaDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, ChinaDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, ChinaUp to now, tuberculosis (TB) remains a global public health problem, posing a serious threat to human health. Traditional methods for analyzing time-varying trends, such as age and period, tend to ignore the poor impact of birth cohorts, which is an important factor in the development of TB. The age-period-cohort (APC) model, a statistical method widely used in recent decades in economics, sociology, and epidemiology, can quantitatively estimate the efficacy of different age, period, and birth cohort groups for TB by separating the effects of these three dimensions and controlling for confounding factors among the time variables. The purpose of this paper is to briefly review the model, focus on the application of the existing APC model in the field of TB, and explain its advantages and disadvantages. This study will help to provides a theoretical basis and reference for using the APC model in TB analysis and prediction.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1486946/fulltuberculosisage-period-cohort modelstime trendsmodel applicationidentification problem
spellingShingle Dan Luo
Fengying Wang
Songhua Chen
Yu Zhang
Wei Wang
Qian Wu
Yuxiao Ling
Yiqing Zhou
Yang Li
Kui Liu
Bin Chen
Application of the age-period-cohort model in tuberculosis
Frontiers in Public Health
tuberculosis
age-period-cohort models
time trends
model application
identification problem
title Application of the age-period-cohort model in tuberculosis
title_full Application of the age-period-cohort model in tuberculosis
title_fullStr Application of the age-period-cohort model in tuberculosis
title_full_unstemmed Application of the age-period-cohort model in tuberculosis
title_short Application of the age-period-cohort model in tuberculosis
title_sort application of the age period cohort model in tuberculosis
topic tuberculosis
age-period-cohort models
time trends
model application
identification problem
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1486946/full
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