Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation
This study was oriented towards encapsulation of S. rebaudiana extract and the study of its release kinetics. The desired encapsulation was achieved by the ionotropic gelation method using sodium alginate and inulin of polymeric constituents. Characterization of the capsules was performed by microme...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2018/6354924 |
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| _version_ | 1832561823896829952 |
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| author | Juan Pablo Quintal Martínez Jorge Carlos Ruiz Ruiz Maira Rubí Segura Campos |
| author_facet | Juan Pablo Quintal Martínez Jorge Carlos Ruiz Ruiz Maira Rubí Segura Campos |
| author_sort | Juan Pablo Quintal Martínez |
| collection | DOAJ |
| description | This study was oriented towards encapsulation of S. rebaudiana extract and the study of its release kinetics. The desired encapsulation was achieved by the ionotropic gelation method using sodium alginate and inulin of polymeric constituents. Characterization of the capsules was performed by micrometric properties, encapsulation efficiency, in vitro extract release analysis, and biological activity of released extract. The in vitro release profiles from different capsules were applied on different kinetic models. The prepared capsules were found spherical in shape with diameters ranging from 2.07 to 2.63 mm, having the encapsulation efficiencies of 43.77% and 56.53% for phenolic compounds and steviol glycosides, respectively. The best-fit model with the highest correlation coefficient was observed in the Ritger–Peppas model, indicating diffusion controlled principle. The release exponent n value obtained from the Korsmeyer–Peppas model varied between 0.2273 and 1.1719, confirming that the mechanism of S. rebaudiana extract bioactive compounds release was diffusion controlled. |
| format | Article |
| id | doaj-art-2a1518ca18a04308a5299de38cac0610 |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-2a1518ca18a04308a5299de38cac06102025-02-03T01:24:06ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422018-01-01201810.1155/2018/63549246354924Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic GelationJuan Pablo Quintal Martínez0Jorge Carlos Ruiz Ruiz1Maira Rubí Segura Campos2Facultad de Ingeniería Química, Universidad Autónoma de Yucatán, Periférico Norte km. 33.5, Tablaje Catastral 13615, Col. Chuburná de Hidalgo Inn, 97203 Mérida, YUC, MexicoEscuela de Nutrición, Universidad Anáhuac Mayab, 97310 Mérida, YUC, MexicoFacultad de Ingeniería Química, Universidad Autónoma de Yucatán, Periférico Norte km. 33.5, Tablaje Catastral 13615, Col. Chuburná de Hidalgo Inn, 97203 Mérida, YUC, MexicoThis study was oriented towards encapsulation of S. rebaudiana extract and the study of its release kinetics. The desired encapsulation was achieved by the ionotropic gelation method using sodium alginate and inulin of polymeric constituents. Characterization of the capsules was performed by micrometric properties, encapsulation efficiency, in vitro extract release analysis, and biological activity of released extract. The in vitro release profiles from different capsules were applied on different kinetic models. The prepared capsules were found spherical in shape with diameters ranging from 2.07 to 2.63 mm, having the encapsulation efficiencies of 43.77% and 56.53% for phenolic compounds and steviol glycosides, respectively. The best-fit model with the highest correlation coefficient was observed in the Ritger–Peppas model, indicating diffusion controlled principle. The release exponent n value obtained from the Korsmeyer–Peppas model varied between 0.2273 and 1.1719, confirming that the mechanism of S. rebaudiana extract bioactive compounds release was diffusion controlled.http://dx.doi.org/10.1155/2018/6354924 |
| spellingShingle | Juan Pablo Quintal Martínez Jorge Carlos Ruiz Ruiz Maira Rubí Segura Campos Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation Advances in Materials Science and Engineering |
| title | Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation |
| title_full | Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation |
| title_fullStr | Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation |
| title_full_unstemmed | Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation |
| title_short | Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation |
| title_sort | release kinetic studies of stevia rebaudiana extract capsules from sodium alginate and inulin by ionotropic gelation |
| url | http://dx.doi.org/10.1155/2018/6354924 |
| work_keys_str_mv | AT juanpabloquintalmartinez releasekineticstudiesofsteviarebaudianaextractcapsulesfromsodiumalginateandinulinbyionotropicgelation AT jorgecarlosruizruiz releasekineticstudiesofsteviarebaudianaextractcapsulesfromsodiumalginateandinulinbyionotropicgelation AT mairarubiseguracampos releasekineticstudiesofsteviarebaudianaextractcapsulesfromsodiumalginateandinulinbyionotropicgelation |