Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting

We ascertained the prevalence of resistant hypertension (RH) among blacks and determined whether RH patients are at greater risk for obstructive sleep apnea (OSA) than hypertensives. Method. Data emanated from Metabolic Syndrome Outcome Study (MetSO), a study investigating metabolic syndrome among...

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Main Authors: M. Demede, A. Pandey, F. Zizi, R. Bachmann, M. Donat, S. I. McFarlane, G. Jean-Louis, G. Ogedegbe
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.4061/2011/340929
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author M. Demede
A. Pandey
F. Zizi
R. Bachmann
M. Donat
S. I. McFarlane
G. Jean-Louis
G. Ogedegbe
author_facet M. Demede
A. Pandey
F. Zizi
R. Bachmann
M. Donat
S. I. McFarlane
G. Jean-Louis
G. Ogedegbe
author_sort M. Demede
collection DOAJ
description We ascertained the prevalence of resistant hypertension (RH) among blacks and determined whether RH patients are at greater risk for obstructive sleep apnea (OSA) than hypertensives. Method. Data emanated from Metabolic Syndrome Outcome Study (MetSO), a study investigating metabolic syndrome among blacks in the primary-care setting. Sample of 200 patients (mean age = 63 ± 13 years; female = 61%) with a diagnosis of hypertension provided subjective and clinical data. RH was defined using the JNC 7and European Society guidelines. We assessed OSA risk using the Apnea Risk Evaluation System ARES), defining high risk as a total ARES score ≥6. Results. Overall, 26% met criteria for RH and 40% were at high OSA risk. Logistic regression analysis, adjusting for effects of age, gender, and medical co morbidities, showed that patients with RH were nearly 2.5 times more likely to be at high OSA risk, relative to those with hypertension (OR = 2.46, 95% CI: 1.03–5.88, P<.05). Conclusion. Our findings show that the prevalence of RH among blacks fell within the range of RH for the general hypertensive population (3–29%). However, patients with RH were at significantly greater risk of OSA compared to patients with hypertension.
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spelling doaj-art-2a05ad1c491f41bc981fe50e976fc60f2025-02-03T06:12:38ZengWileyInternational Journal of Hypertension2090-03922011-01-01201110.4061/2011/340929340929Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care SettingM. Demede0A. Pandey1F. Zizi2R. Bachmann3M. Donat4S. I. McFarlane5G. Jean-Louis6G. Ogedegbe7Brooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USABrooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USABrooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USABrooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USABrooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USADepartment of Endocrinology, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USABrooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USACenter for Healthful Behavior Change, Division of Internal Medicine, NYU Medical Center, New York, NY 10016, USAWe ascertained the prevalence of resistant hypertension (RH) among blacks and determined whether RH patients are at greater risk for obstructive sleep apnea (OSA) than hypertensives. Method. Data emanated from Metabolic Syndrome Outcome Study (MetSO), a study investigating metabolic syndrome among blacks in the primary-care setting. Sample of 200 patients (mean age = 63 ± 13 years; female = 61%) with a diagnosis of hypertension provided subjective and clinical data. RH was defined using the JNC 7and European Society guidelines. We assessed OSA risk using the Apnea Risk Evaluation System ARES), defining high risk as a total ARES score ≥6. Results. Overall, 26% met criteria for RH and 40% were at high OSA risk. Logistic regression analysis, adjusting for effects of age, gender, and medical co morbidities, showed that patients with RH were nearly 2.5 times more likely to be at high OSA risk, relative to those with hypertension (OR = 2.46, 95% CI: 1.03–5.88, P<.05). Conclusion. Our findings show that the prevalence of RH among blacks fell within the range of RH for the general hypertensive population (3–29%). However, patients with RH were at significantly greater risk of OSA compared to patients with hypertension.http://dx.doi.org/10.4061/2011/340929
spellingShingle M. Demede
A. Pandey
F. Zizi
R. Bachmann
M. Donat
S. I. McFarlane
G. Jean-Louis
G. Ogedegbe
Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting
International Journal of Hypertension
title Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting
title_full Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting
title_fullStr Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting
title_full_unstemmed Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting
title_short Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting
title_sort resistant hypertension and obstructive sleep apnea in the primary care setting
url http://dx.doi.org/10.4061/2011/340929
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