On a mathematical model of tumor growth based on cancer stem cells
We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution ofdifferent subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth eq...
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Main Author: | |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2012-11-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.263 |
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Summary: | We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution ofdifferent subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth equation is introduced to model the evolution of the moving boundary. The system includes non-local terms of integral type in the coefficients. Under some restrictions in the parameters we show thatthere exists a unique homogeneous steady state which is stable. |
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ISSN: | 1551-0018 |