On a mathematical model of tumor growth based on cancer stem cells

We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution ofdifferent subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth eq...

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Bibliographic Details
Main Author: J. Ignacio Tello
Format: Article
Language:English
Published: AIMS Press 2012-11-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.263
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Summary:We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution ofdifferent subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth equation is introduced to model the evolution of the moving boundary. The system includes non-local terms of integral type in the coefficients. Under some restrictions in the parameters we show thatthere exists a unique homogeneous steady state which is stable.
ISSN:1551-0018