Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination
Malignant melanoma (MM) and blue nevi of the uterine cervix are an extremely rare neoplasm, probably derived from embryologic migration of melanocytes from the neural crest. MM displays aggressive behavior with a poor prognosis. We report the case of a 76-year-old postmenopausal woman abnormal vagin...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2012/986542 |
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| author | David Parada Karla B. Peña Frances Riu |
| author_facet | David Parada Karla B. Peña Frances Riu |
| author_sort | David Parada |
| collection | DOAJ |
| description | Malignant melanoma (MM) and blue nevi of the uterine cervix are an extremely rare neoplasm, probably derived from embryologic migration of melanocytes from the neural crest. MM displays aggressive behavior with a poor prognosis. We report the case of a 76-year-old postmenopausal woman abnormal vaginal bleeding. She underwent a hysterectomy and bilateral salpingo-oophorectomy with paraaortic-iliac lymphadenectomy. Histopathological and immunohistochemical studies were consistent with the diagnosis of MM and blue nevi in the uterine cervix. Although it is extremely rare, this case suggests that MM of the uterine cervix should be considered in the differential diagnosis of undifferentiated neoplasm. Early diagnosis is essential in order to warrant a better prognosis, although there are no cases of cure described. |
| format | Article |
| id | doaj-art-29e3057e2c234199badfbb73ef89f2dc |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-29e3057e2c234199badfbb73ef89f2dc2025-02-03T01:10:34ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/986542986542Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual CombinationDavid Parada0Karla B. Peña1Frances Riu2Departament de Anatomía Patològica, Hospital Universitari Sant Joan de Reus, Reus, 43201 Tarragona, SpainDepartament de Anatomía Patològica, Hospital Universitari Sant Joan de Reus, Reus, 43201 Tarragona, SpainDepartament de Anatomía Patològica, Hospital Universitari Sant Joan de Reus, Reus, 43201 Tarragona, SpainMalignant melanoma (MM) and blue nevi of the uterine cervix are an extremely rare neoplasm, probably derived from embryologic migration of melanocytes from the neural crest. MM displays aggressive behavior with a poor prognosis. We report the case of a 76-year-old postmenopausal woman abnormal vaginal bleeding. She underwent a hysterectomy and bilateral salpingo-oophorectomy with paraaortic-iliac lymphadenectomy. Histopathological and immunohistochemical studies were consistent with the diagnosis of MM and blue nevi in the uterine cervix. Although it is extremely rare, this case suggests that MM of the uterine cervix should be considered in the differential diagnosis of undifferentiated neoplasm. Early diagnosis is essential in order to warrant a better prognosis, although there are no cases of cure described.http://dx.doi.org/10.1155/2012/986542 |
| spellingShingle | David Parada Karla B. Peña Frances Riu Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination Case Reports in Pathology |
| title | Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination |
| title_full | Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination |
| title_fullStr | Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination |
| title_full_unstemmed | Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination |
| title_short | Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination |
| title_sort | coexisting malignant melanoma and blue nevus of the uterine cervix an unusual combination |
| url | http://dx.doi.org/10.1155/2012/986542 |
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