PREVALENCE AND FACTORS ASSOCIATED WITH BACTERIAL INFECTION IN CIRRHOTIC PATIENTS IN TOGO
ABSTRACT Objectives: to determine the prevalence and identify the factors associated with bacterial infection in cirrhotic patients in Togo. Methods: This was a descriptive and analytical cross-sectional study, with retrospective data collection, conducted in the hepato-gastroenterology department...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)
2025-07-01
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| Series: | Arquivos de Gastroenterologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032025000100504&lng=en&tlng=en |
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| Summary: | ABSTRACT Objectives: to determine the prevalence and identify the factors associated with bacterial infection in cirrhotic patients in Togo. Methods: This was a descriptive and analytical cross-sectional study, with retrospective data collection, conducted in the hepato-gastroenterology department of the Campus University Hospital during three years. All patients hospitalized in the department during this period and diagnosed with cirrhosis were included in the study. Results: During the study period, 270 patients were hospitalized for cirrhosis including 63 cases of bacterial infection, a prevalence of 23.3%. Bacterial infections were represented by spontaneous infection of ascites fluid (15.9%) followed by urinary tract infection (4%). The median length of hospital stay was 10 days Thirty-six of the patients with infection died in hospital, corresponding to a mortality rate of 57.1%. Factors associated with bacterial infection were ascites (P=0.017; OR=4.56), hepatic encephalopathy (P=0.02; OR=4.32), a prothrombin level below 25% (P=0.002; OR=9.67) and a high MELD score (P=0.03; OR=0.93). Conclusion: Bacterial infection occurs in advanced cirrhosis and is associated with a poor prognosis. |
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| ISSN: | 1678-4219 |