Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario
Clinical records of 222 patients with proven Crohn's disease identified at Queen's University Medical School in Kingston, Ontario from 1966 to 1984 were reviewed. Four clinical patterns were identified. Ileocolic disease (44%) was most trequent. Small intestinal involvement alone occurred...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
1988-01-01
|
| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1988/132031 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556730040451072 |
|---|---|
| author | William T. Depew Jose Medeiros Ivan T. Beck Laurington R. Dacosta Aubrey Groll |
| author_facet | William T. Depew Jose Medeiros Ivan T. Beck Laurington R. Dacosta Aubrey Groll |
| author_sort | William T. Depew |
| collection | DOAJ |
| description | Clinical records of 222 patients with proven Crohn's disease identified
at Queen's University Medical School in Kingston, Ontario from 1966 to 1984 were
reviewed. Four clinical patterns were identified. Ileocolic disease (44%) was most
trequent. Small intestinal involvement alone occurred in 30% while colonic
involvement alone was documented in 18%. Gastroduodenal Crohn's disease was
diagnosed in 8.5%, but in all such patients there was involvement of additional small
or large bowel. Females (57%) out-numbered males (43%) with a female to male ratio
of 1.3. The age range at diagnosis was seven to 73 years and 177 patients (80%) were
diagnosed between the ages of 11 and 40 years. Patients with colonic disease only
tended to be older and had fewer obstructive episodes, fewer surgical resections and
more gross rectal bleeding. Patients with gascroduodenal disease were more often
male, usually had additional small bowel involvement, experienced more local
complications and required more surgical intervention than the ocher patterns. Only
one patient was identified with disease restricted to the anorectum. Patients in this
series were followed from two months to 24 years. The mean duration of follow-up
was 4.9 years. The frequency of complications and the necessity for surgery were
similar to other reported series. None of the patients had either large or small bowel
cancer during the follow-up period and there were no deaths related directly to
Crohn's disease, its complications or related surgery. |
| format | Article |
| id | doaj-art-29cb8162a3204c7e8bcf0fd76e8f5502 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1988-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-29cb8162a3204c7e8bcf0fd76e8f55022025-02-03T05:44:27ZengWileyCanadian Journal of Gastroenterology0835-79001988-01-012310711610.1155/1988/132031Clinical Presentation and Course of Crohn's Disease in Southeastern OntarioWilliam T. Depew0Jose Medeiros1Ivan T. Beck2Laurington R. Dacosta3Aubrey Groll4Gastrointestinal Diseasc Research Unit, Queen’s University Medical School, Kingston, Ontario, CanadaGastrointestinal Diseasc Research Unit, Queen’s University Medical School, Kingston, Ontario, CanadaGastrointestinal Diseasc Research Unit, Queen’s University Medical School, Kingston, Ontario, CanadaGastrointestinal Diseasc Research Unit, Queen’s University Medical School, Kingston, Ontario, CanadaGastrointestinal Diseasc Research Unit, Queen’s University Medical School, Kingston, Ontario, CanadaClinical records of 222 patients with proven Crohn's disease identified at Queen's University Medical School in Kingston, Ontario from 1966 to 1984 were reviewed. Four clinical patterns were identified. Ileocolic disease (44%) was most trequent. Small intestinal involvement alone occurred in 30% while colonic involvement alone was documented in 18%. Gastroduodenal Crohn's disease was diagnosed in 8.5%, but in all such patients there was involvement of additional small or large bowel. Females (57%) out-numbered males (43%) with a female to male ratio of 1.3. The age range at diagnosis was seven to 73 years and 177 patients (80%) were diagnosed between the ages of 11 and 40 years. Patients with colonic disease only tended to be older and had fewer obstructive episodes, fewer surgical resections and more gross rectal bleeding. Patients with gascroduodenal disease were more often male, usually had additional small bowel involvement, experienced more local complications and required more surgical intervention than the ocher patterns. Only one patient was identified with disease restricted to the anorectum. Patients in this series were followed from two months to 24 years. The mean duration of follow-up was 4.9 years. The frequency of complications and the necessity for surgery were similar to other reported series. None of the patients had either large or small bowel cancer during the follow-up period and there were no deaths related directly to Crohn's disease, its complications or related surgery.http://dx.doi.org/10.1155/1988/132031 |
| spellingShingle | William T. Depew Jose Medeiros Ivan T. Beck Laurington R. Dacosta Aubrey Groll Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario Canadian Journal of Gastroenterology |
| title | Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario |
| title_full | Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario |
| title_fullStr | Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario |
| title_full_unstemmed | Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario |
| title_short | Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario |
| title_sort | clinical presentation and course of crohn s disease in southeastern ontario |
| url | http://dx.doi.org/10.1155/1988/132031 |
| work_keys_str_mv | AT williamtdepew clinicalpresentationandcourseofcrohnsdiseaseinsoutheasternontario AT josemedeiros clinicalpresentationandcourseofcrohnsdiseaseinsoutheasternontario AT ivantbeck clinicalpresentationandcourseofcrohnsdiseaseinsoutheasternontario AT lauringtonrdacosta clinicalpresentationandcourseofcrohnsdiseaseinsoutheasternontario AT aubreygroll clinicalpresentationandcourseofcrohnsdiseaseinsoutheasternontario |