Stem Cells Applications in Regenerative Medicine and Disease Therapeutics
Regenerative medicine, the most recent and emerging branch of medical science, deals with functional restoration of tissues or organs for the patient suffering from severe injuries or chronic disease. The spectacular progress in the field of stem cell research has laid the foundation for cell based...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Cell Biology |
| Online Access: | http://dx.doi.org/10.1155/2016/6940283 |
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| _version_ | 1832551383528636416 |
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| author | Ranjeet Singh Mahla |
| author_facet | Ranjeet Singh Mahla |
| author_sort | Ranjeet Singh Mahla |
| collection | DOAJ |
| description | Regenerative medicine, the most recent and emerging branch of medical science, deals with functional restoration of tissues or organs for the patient suffering from severe injuries or chronic disease. The spectacular progress in the field of stem cell research has laid the foundation for cell based therapies of disease which cannot be cured by conventional medicines. The indefinite self-renewal and potential to differentiate into other types of cells represent stem cells as frontiers of regenerative medicine. The transdifferentiating potential of stem cells varies with source and according to that regenerative applications also change. Advancements in gene editing and tissue engineering technology have endorsed the ex vivo remodelling of stem cells grown into 3D organoids and tissue structures for personalized applications. This review outlines the most recent advancement in transplantation and tissue engineering technologies of ESCs, TSPSCs, MSCs, UCSCs, BMSCs, and iPSCs in regenerative medicine. Additionally, this review also discusses stem cells regenerative application in wildlife conservation. |
| format | Article |
| id | doaj-art-299fd671a7944b77afff0653031efe6f |
| institution | Kabale University |
| issn | 1687-8876 1687-8884 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Cell Biology |
| spelling | doaj-art-299fd671a7944b77afff0653031efe6f2025-02-03T06:01:37ZengWileyInternational Journal of Cell Biology1687-88761687-88842016-01-01201610.1155/2016/69402836940283Stem Cells Applications in Regenerative Medicine and Disease TherapeuticsRanjeet Singh Mahla0Department of Biological Sciences, Indian Institute of Science Education and Research (IISER), Bhopal, Madhya Pradesh 462066, IndiaRegenerative medicine, the most recent and emerging branch of medical science, deals with functional restoration of tissues or organs for the patient suffering from severe injuries or chronic disease. The spectacular progress in the field of stem cell research has laid the foundation for cell based therapies of disease which cannot be cured by conventional medicines. The indefinite self-renewal and potential to differentiate into other types of cells represent stem cells as frontiers of regenerative medicine. The transdifferentiating potential of stem cells varies with source and according to that regenerative applications also change. Advancements in gene editing and tissue engineering technology have endorsed the ex vivo remodelling of stem cells grown into 3D organoids and tissue structures for personalized applications. This review outlines the most recent advancement in transplantation and tissue engineering technologies of ESCs, TSPSCs, MSCs, UCSCs, BMSCs, and iPSCs in regenerative medicine. Additionally, this review also discusses stem cells regenerative application in wildlife conservation.http://dx.doi.org/10.1155/2016/6940283 |
| spellingShingle | Ranjeet Singh Mahla Stem Cells Applications in Regenerative Medicine and Disease Therapeutics International Journal of Cell Biology |
| title | Stem Cells Applications in Regenerative Medicine and Disease Therapeutics |
| title_full | Stem Cells Applications in Regenerative Medicine and Disease Therapeutics |
| title_fullStr | Stem Cells Applications in Regenerative Medicine and Disease Therapeutics |
| title_full_unstemmed | Stem Cells Applications in Regenerative Medicine and Disease Therapeutics |
| title_short | Stem Cells Applications in Regenerative Medicine and Disease Therapeutics |
| title_sort | stem cells applications in regenerative medicine and disease therapeutics |
| url | http://dx.doi.org/10.1155/2016/6940283 |
| work_keys_str_mv | AT ranjeetsinghmahla stemcellsapplicationsinregenerativemedicineanddiseasetherapeutics |