Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy

Autoimmune cytopenias (AICs) are frequently associated with chronic lymphocytic leukemia (CLL). The most common of these AICs is autoimmune hemolytic anemia (AIHA); the second most is immune thrombocytopenia (ITP). Here, we report on a patient with CLL-associated ITP, with thrombocytopenia refractor...

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Main Authors: Juárez Salcedo Luis Miguel, Gil-Fernández Juan José
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/9538920
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author Juárez Salcedo Luis Miguel
Gil-Fernández Juan José
author_facet Juárez Salcedo Luis Miguel
Gil-Fernández Juan José
author_sort Juárez Salcedo Luis Miguel
collection DOAJ
description Autoimmune cytopenias (AICs) are frequently associated with chronic lymphocytic leukemia (CLL). The most common of these AICs is autoimmune hemolytic anemia (AIHA); the second most is immune thrombocytopenia (ITP). Here, we report on a patient with CLL-associated ITP, with thrombocytopenia refractory to corticosteroids and intravenous immunoglobulins, in which continuous oral treatment with Eltrombopag allowed initiation and maintenance of an oral anticoagulation treatment with Acenocoumarol that was indicated because of a severe arrhythmogenic cardiomyopathy.
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institution Kabale University
issn 2090-6560
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publishDate 2017-01-01
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series Case Reports in Hematology
spelling doaj-art-298a7d578f684143abcfb7ffbbf02c8b2025-02-03T01:11:07ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/95389209538920Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe CardiomyopathyJuárez Salcedo Luis Miguel0Gil-Fernández Juan José1Division of Hematology, Principe de Asturias University Hospital, Madrid, SpainDivision of Hematology, Principe de Asturias University Hospital, Madrid, SpainAutoimmune cytopenias (AICs) are frequently associated with chronic lymphocytic leukemia (CLL). The most common of these AICs is autoimmune hemolytic anemia (AIHA); the second most is immune thrombocytopenia (ITP). Here, we report on a patient with CLL-associated ITP, with thrombocytopenia refractory to corticosteroids and intravenous immunoglobulins, in which continuous oral treatment with Eltrombopag allowed initiation and maintenance of an oral anticoagulation treatment with Acenocoumarol that was indicated because of a severe arrhythmogenic cardiomyopathy.http://dx.doi.org/10.1155/2017/9538920
spellingShingle Juárez Salcedo Luis Miguel
Gil-Fernández Juan José
Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy
Case Reports in Hematology
title Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy
title_full Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy
title_fullStr Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy
title_full_unstemmed Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy
title_short Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy
title_sort successful long term use of eltrombopag in a patient with refractory severe thrombocytopenia associated with chronic lymphocytic leukemia that allowed oral anticoagulant treatment for severe cardiomyopathy
url http://dx.doi.org/10.1155/2017/9538920
work_keys_str_mv AT juarezsalcedoluismiguel successfullongtermuseofeltrombopaginapatientwithrefractoryseverethrombocytopeniaassociatedwithchroniclymphocyticleukemiathatallowedoralanticoagulanttreatmentforseverecardiomyopathy
AT gilfernandezjuanjose successfullongtermuseofeltrombopaginapatientwithrefractoryseverethrombocytopeniaassociatedwithchroniclymphocyticleukemiathatallowedoralanticoagulanttreatmentforseverecardiomyopathy