Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis
Deregulated interplay between inflammation and coagulation plays a pivotal role in the pathogenesis of sepsis. Therapeutic approaches that simultaneously target both inflammation and coagulation hold great promise for the treatment of sepsis. Thrombomodulin is an endogenous anticoagulant protein tha...
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Main Authors: | Takayuki Okamoto, Hironobu Tanigami, Koji Suzuki, Motomu Shimaoka |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Critical Care Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2012/614545 |
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