Tanshinone IIA potentiates the therapeutic efficacy of glucocorticoids in lipopolysaccharide-treated HEI-OC1 cells through modulation of the FOXP3/Nrf2 signaling pathway

Tanshinone IIA potentiates the therapeutic efficacy of glucocorticoids in lipopolysaccharide-treated HEI-OC1 cells through modulation of the FOXP3/Nrf2 signaling pathway

Glucocorticoids (GCs) are commonly used to treat sudden sensorineural hearing loss (SSNHL), although some patients are resistant to this therapeutic approach. Clinical studies have demonstrated the efficacy of tanshinone IIA (TA) in combination with GC for managing various human ailments. However, i...

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Bibliographic Details
Main Authors: Li Jie, Zhu Xiaoyan, Ye Shiming, Dong Qi, Hou Jie, Liu Jing, She Wandong
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-11-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
tanshinone IIA
sudden sensorineural hearing loss
glucocorticoid resistance
FOXP3
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024194
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