Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection
Background and Aims. There is no consensus so far regarding the optimal endoscopic method for treatment of small rectal neuroendocrine tumor (NET). The aim of this study was to compare treatment efficacy, safety, and procedure time between endoscopic submucosal resection with band ligation (ESMR-L)...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/6198927 |
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| author | Byoung Wook Bang Jin Seok Park Hyung Kil Kim Yong Woon Shin Kye Sook Kwon Joon Mee Kim |
| author_facet | Byoung Wook Bang Jin Seok Park Hyung Kil Kim Yong Woon Shin Kye Sook Kwon Joon Mee Kim |
| author_sort | Byoung Wook Bang |
| collection | DOAJ |
| description | Background and Aims. There is no consensus so far regarding the optimal endoscopic method for treatment of small rectal neuroendocrine tumor (NET). The aim of this study was to compare treatment efficacy, safety, and procedure time between endoscopic submucosal resection with band ligation (ESMR-L) and endoscopic submucosal dissection (ESD). Methods. We conducted a prospective study of patients who visited Inha University Hospital for endoscopic resection of rectal NET (≦10 mm). Pathological complete resection rate, procedure time, and complications were evaluated. Results. A total of 77 patients were treated by ESMR-L (n=53) or ESD (n=24). En bloc resection was achieved in all patients. A significantly higher pathological complete resection rate was observed in the ESMR-L group (53/53, 100%) than in the ESD group (13/24, 54.2%) (P=0.000). The procedure time of ESD (17.9±9.1 min) was significantly longer compared to that of ESMR-L (5.3±2.8 min) (P=0.000). Conclusions. Considering the clinical efficacy, technical difficulty, and procedure time, the ESMR-L method should be considered as the first-line therapy for the small rectal NET (≤10 mm). ESD should be left as a second-line treatment for the fibrotic lesion which could not be removed using the ESMR-L method. |
| format | Article |
| id | doaj-art-2936001dd66440d5b69aa70f3311d80f |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-2936001dd66440d5b69aa70f3311d80f2025-02-03T05:54:20ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/61989276198927Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal DissectionByoung Wook Bang0Jin Seok Park1Hyung Kil Kim2Yong Woon Shin3Kye Sook Kwon4Joon Mee Kim5Division of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Republic of KoreaDivision of Gastroenterology, Department of Pathology, Inha University School of Medicine, Incheon 22332, Republic of KoreaBackground and Aims. There is no consensus so far regarding the optimal endoscopic method for treatment of small rectal neuroendocrine tumor (NET). The aim of this study was to compare treatment efficacy, safety, and procedure time between endoscopic submucosal resection with band ligation (ESMR-L) and endoscopic submucosal dissection (ESD). Methods. We conducted a prospective study of patients who visited Inha University Hospital for endoscopic resection of rectal NET (≦10 mm). Pathological complete resection rate, procedure time, and complications were evaluated. Results. A total of 77 patients were treated by ESMR-L (n=53) or ESD (n=24). En bloc resection was achieved in all patients. A significantly higher pathological complete resection rate was observed in the ESMR-L group (53/53, 100%) than in the ESD group (13/24, 54.2%) (P=0.000). The procedure time of ESD (17.9±9.1 min) was significantly longer compared to that of ESMR-L (5.3±2.8 min) (P=0.000). Conclusions. Considering the clinical efficacy, technical difficulty, and procedure time, the ESMR-L method should be considered as the first-line therapy for the small rectal NET (≤10 mm). ESD should be left as a second-line treatment for the fibrotic lesion which could not be removed using the ESMR-L method.http://dx.doi.org/10.1155/2016/6198927 |
| spellingShingle | Byoung Wook Bang Jin Seok Park Hyung Kil Kim Yong Woon Shin Kye Sook Kwon Joon Mee Kim Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection Gastroenterology Research and Practice |
| title | Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection |
| title_full | Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection |
| title_fullStr | Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection |
| title_full_unstemmed | Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection |
| title_short | Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection |
| title_sort | endoscopic resection for small rectal neuroendocrine tumors comparison of endoscopic submucosal resection with band ligation and endoscopic submucosal dissection |
| url | http://dx.doi.org/10.1155/2016/6198927 |
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