Polymers for Cardiovascular Stent Coatings
Polymers have found widespread applications in cardiology, in particular in coronary vascular intervention as stent platforms (scaffolds) and coating matrices for drug-eluting stents. Apart from permanent polymers, current research is focussing on biodegradable polymers. Since they degrade once thei...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2015/782653 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832548105237561344 |
|---|---|
| author | Anne Strohbach Raila Busch |
| author_facet | Anne Strohbach Raila Busch |
| author_sort | Anne Strohbach |
| collection | DOAJ |
| description | Polymers have found widespread applications in cardiology, in particular in coronary vascular intervention as stent platforms (scaffolds) and coating matrices for drug-eluting stents. Apart from permanent polymers, current research is focussing on biodegradable polymers. Since they degrade once their function is fulfilled, their use might contribute to the reduction of adverse events like in-stent restenosis, late stent-thrombosis, and hypersensitivity reactions. After reviewing current literature concerning polymers used for cardiovascular applications, this review deals with parameters of tissue and blood cell functions which should be considered to evaluate biocompatibility of stent polymers in order to enhance physiological appropriate properties. The properties of the substrate on which vascular cells are placed can have a large impact on cell morphology, differentiation, motility, and fate. Finally, methods to assess these parameters under physiological conditions will be summarized. |
| format | Article |
| id | doaj-art-29059ddcdacf4bb8bb5ba52660affde4 |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-29059ddcdacf4bb8bb5ba52660affde42025-02-03T06:42:13ZengWileyInternational Journal of Polymer Science1687-94221687-94302015-01-01201510.1155/2015/782653782653Polymers for Cardiovascular Stent CoatingsAnne Strohbach0Raila Busch1Ernst-Moritz-Arndt University, Clinic for Internal Medicine B, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, GermanyErnst-Moritz-Arndt University, Clinic for Internal Medicine B, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, GermanyPolymers have found widespread applications in cardiology, in particular in coronary vascular intervention as stent platforms (scaffolds) and coating matrices for drug-eluting stents. Apart from permanent polymers, current research is focussing on biodegradable polymers. Since they degrade once their function is fulfilled, their use might contribute to the reduction of adverse events like in-stent restenosis, late stent-thrombosis, and hypersensitivity reactions. After reviewing current literature concerning polymers used for cardiovascular applications, this review deals with parameters of tissue and blood cell functions which should be considered to evaluate biocompatibility of stent polymers in order to enhance physiological appropriate properties. The properties of the substrate on which vascular cells are placed can have a large impact on cell morphology, differentiation, motility, and fate. Finally, methods to assess these parameters under physiological conditions will be summarized.http://dx.doi.org/10.1155/2015/782653 |
| spellingShingle | Anne Strohbach Raila Busch Polymers for Cardiovascular Stent Coatings International Journal of Polymer Science |
| title | Polymers for Cardiovascular Stent Coatings |
| title_full | Polymers for Cardiovascular Stent Coatings |
| title_fullStr | Polymers for Cardiovascular Stent Coatings |
| title_full_unstemmed | Polymers for Cardiovascular Stent Coatings |
| title_short | Polymers for Cardiovascular Stent Coatings |
| title_sort | polymers for cardiovascular stent coatings |
| url | http://dx.doi.org/10.1155/2015/782653 |
| work_keys_str_mv | AT annestrohbach polymersforcardiovascularstentcoatings AT railabusch polymersforcardiovascularstentcoatings |