New-Onset Palmar Psoriasis Following mRNA COVID-19 Vaccination: A Case Report

Haya Fahad A Alzamami,1 Omer A AlSulaiman,1 Gaeda Khaled I Alkaltham,2 Hadeel K Alotaibi3 1Department of Dermatology, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia; 2Department of Dermatology, Ministry of Health, Dammam, Saudi Arabia; 3College of Medicine, Imam Ab...

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Main Authors: Alzamami HFA, AlSulaiman OA, Alkaltham GKI, Alotaibi HK
Format: Article
Language:English
Published: Dove Medical Press 2025-08-01
Series:International Medical Case Reports Journal
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Online Access:https://www.dovepress.com/new-onset-palmar-psoriasis-following-mrna-covid-19-vaccination-a-case--peer-reviewed-fulltext-article-IMCRJ
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Summary:Haya Fahad A Alzamami,1 Omer A AlSulaiman,1 Gaeda Khaled I Alkaltham,2 Hadeel K Alotaibi3 1Department of Dermatology, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia; 2Department of Dermatology, Ministry of Health, Dammam, Saudi Arabia; 3College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Hadeel K Alotaibi, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, P.O. Box 34224, Saudi Arabia, Tel +966555197355, Email hadeellkhaled@gmail.comAbstract: Palmoplantar psoriasis is a rare, chronic, localized variant of psoriasis. It represents 3– 4% of all psoriasis cases and is characterized by hyperkeratotic or desquamative erythematous plaques with fissures and erosions exhibiting acral distribution. Occasionally, superimposed sterile pustulations may also occur. New-onset psoriasis and various clinical subtypes of psoriasis exacerbation have been reported following the administration of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines, with plaque-type psoriasis being the most common. However, palmar psoriasis has not yet been reported in association with COVID-19 vaccination. Herein, we present a case of new-onset palmar psoriasis along with nail changes following mRNA COVID-19 vaccination, which was further exacerbated following successive vaccine doses.Keywords: psoriasis, palmoplantar, mRNA vaccine, COVID-19
ISSN:1179-142X