Artemisia capillaris with two novel active compounds, Kawarayomogin I and II, inhibits HYBID (KIAA1199) expression as well as hyaluronic acid degradation

Artemisia capillaris with two novel active compounds, Kawarayomogin I and II, inhibits HYBID (KIAA1199) expression as well as hyaluronic acid degradation

Abstract Hyaluronic acid (HA) is an important component of the skin’s extracellular matrix, and its degradation leads to wrinkles. Hyaluronan-binding protein involved in hyaluronan depolymerization (HYBID) is the main factor responsible for HA degradation in dermis. This study aimed to identify natu...

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Bibliographic Details
Main Authors: Kazal Boron Biswas, Yuka Kawai, Satoshi Nakagawa, Kyoko Kanai, Hiroyuki Kojima, Teruaki Masutani, Masayoshi Oyama, Arunasiri Iddamalgoda, Kotaro Sakamoto
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Artemisia capillaris flower extract
HYBID
Hyaluronic acid
Kawarayomogin
miR-486-5p
Online Access:https://doi.org/10.1038/s41598-025-86320-4
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