Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis

Zoledronate or denosumab treatment is beneficial for cancer patients with bone metastasis. However, each agent may trigger atypical femoral fractures. Incomplete atypical femoral fractures can be successfully treated with prophylactic intramedullary nailing. On the other hand, intramedullary nailing...

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Main Authors: Hironari Tamiya, Hiroki Hagizawa, Takaaki Nakai, Yoshinori Imura, Takaaki Tanaka, Kazuya Oshima, Toshikazu Ito, Norifumi Naka, Shigeyuki Kuratsu
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2018/7862516
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author Hironari Tamiya
Hiroki Hagizawa
Takaaki Nakai
Yoshinori Imura
Takaaki Tanaka
Kazuya Oshima
Toshikazu Ito
Norifumi Naka
Shigeyuki Kuratsu
author_facet Hironari Tamiya
Hiroki Hagizawa
Takaaki Nakai
Yoshinori Imura
Takaaki Tanaka
Kazuya Oshima
Toshikazu Ito
Norifumi Naka
Shigeyuki Kuratsu
author_sort Hironari Tamiya
collection DOAJ
description Zoledronate or denosumab treatment is beneficial for cancer patients with bone metastasis. However, each agent may trigger atypical femoral fractures. Incomplete atypical femoral fractures can be successfully treated with prophylactic intramedullary nailing. On the other hand, intramedullary nailing for displaced atypical femoral fractures occasionally causes problems with regard to bone healing, resulting in long-term treatment. In cancer patients with poor prognosis who experience atypical femoral fractures, improvement in activities of daily living should be the priority. Thus, we performed endoprosthetic reconstruction for a displaced atypical femoral fracture in a breast cancer patient with poor prognosis to enable walking in the early stage after the operation. Two weeks after the operation, she could successfully walk. The postoperative Musculoskeletal Tumor Society score was 47%, and it had improved to almost the preoperative level before injury (50%). In conclusion, endoprosthetic reconstruction for displaced atypical femoral fractures may be a first-line treatment approach to acquire early postoperative walking ability for improving activities of daily living in cancer patients with poor prognosis.
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institution Kabale University
issn 2090-6749
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Orthopedics
spelling doaj-art-289f0f2b064f42c6969106657881421b2025-02-03T06:13:23ZengWileyCase Reports in Orthopedics2090-67492090-67572018-01-01201810.1155/2018/78625167862516Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor PrognosisHironari Tamiya0Hiroki Hagizawa1Takaaki Nakai2Yoshinori Imura3Takaaki Tanaka4Kazuya Oshima5Toshikazu Ito6Norifumi Naka7Shigeyuki Kuratsu8Department of Orthopedic Surgery, Bellland General Hospital, 500-3 Higashiyama, Naka-ku, Sakai, 599-8247 Osaka, JapanDepartment of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka City, 541-8567 Osaka, JapanDepartment of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka City, 541-8567 Osaka, JapanDepartment of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka City, 541-8567 Osaka, JapanDepartment of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka City, 541-8567 Osaka, JapanDepartment of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka City, 541-8567 Osaka, JapanDepartment of Surgery, Rinku Genaral Medical Center, 2-23 Rinku Ourai Kita, Izumisano, 598-8577 Osaka, JapanDepartment of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka City, 541-8567 Osaka, JapanDepartment of Orthopedic Surgery, Bellland General Hospital, 500-3 Higashiyama, Naka-ku, Sakai, 599-8247 Osaka, JapanZoledronate or denosumab treatment is beneficial for cancer patients with bone metastasis. However, each agent may trigger atypical femoral fractures. Incomplete atypical femoral fractures can be successfully treated with prophylactic intramedullary nailing. On the other hand, intramedullary nailing for displaced atypical femoral fractures occasionally causes problems with regard to bone healing, resulting in long-term treatment. In cancer patients with poor prognosis who experience atypical femoral fractures, improvement in activities of daily living should be the priority. Thus, we performed endoprosthetic reconstruction for a displaced atypical femoral fracture in a breast cancer patient with poor prognosis to enable walking in the early stage after the operation. Two weeks after the operation, she could successfully walk. The postoperative Musculoskeletal Tumor Society score was 47%, and it had improved to almost the preoperative level before injury (50%). In conclusion, endoprosthetic reconstruction for displaced atypical femoral fractures may be a first-line treatment approach to acquire early postoperative walking ability for improving activities of daily living in cancer patients with poor prognosis.http://dx.doi.org/10.1155/2018/7862516
spellingShingle Hironari Tamiya
Hiroki Hagizawa
Takaaki Nakai
Yoshinori Imura
Takaaki Tanaka
Kazuya Oshima
Toshikazu Ito
Norifumi Naka
Shigeyuki Kuratsu
Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis
Case Reports in Orthopedics
title Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis
title_full Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis
title_fullStr Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis
title_full_unstemmed Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis
title_short Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis
title_sort endoprosthetic reconstruction for a displaced atypical femoral fracture in a cancer patient with poor prognosis
url http://dx.doi.org/10.1155/2018/7862516
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