Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes
Background: Antibiotics were extensively used in the pigeon breeding industry previously to promote growth and prevent disease, leading to the spread of antibiotic-resistant genes (ARGs) in gut microbes, which has become a major public health concern. Methods: A metagenomic analysis was performed to...
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2025-01-01
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| author | Wei Dai Haicong Zhu Junhong Chen Hui Chen Dingzhen Dai Jian Wu |
| author_facet | Wei Dai Haicong Zhu Junhong Chen Hui Chen Dingzhen Dai Jian Wu |
| author_sort | Wei Dai |
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| description | Background: Antibiotics were extensively used in the pigeon breeding industry previously to promote growth and prevent disease, leading to the spread of antibiotic-resistant genes (ARGs) in gut microbes, which has become a major public health concern. Methods: A metagenomic analysis was performed to investigate the gut microbial communities and ARGs in young and older pigeons in Nanjing, Jiangsu Province, China. Results: There were obviously distinct gut microbiota and functional compositions between young and older pigeons. Both Pseudomonadota and Uroviricota were dominant in young and older pigeons. Although sharing 24 gut microbiota phyla between young and older pigeons, Bacillota and Pseudomonadota were the dominant microbial phyla in them, respectively. Besides the shared metabolic pathways and biosynthesis of secondary metabolites, biosynthesis of amino acids was the most abundant Kyoto Encyclopedia of Genes and Genomes (KEGG) function in young pigeons, while microbial metabolism in diverse environments was abundant in older pigeons. A total of 142 ARGs conferring multidrug resistance, tetracycline, and aminoglycoside resistance were identified; the most abundant gene in young pigeons was tetracycline-tetW, while in older pigeons, it was multidrug-acrB. Conclusions: Our findings revealed significant differences in the gut microbial communities and ARGs between young and older pigeons. This study enhances our understanding of pigeon gut microbiota and antibiotic resistomes, contributing to knowledge-based sustainable pigeon meat production. |
| format | Article |
| id | doaj-art-28937c7ec436426a8e99b95a9912d574 |
| institution | Kabale University |
| issn | 2079-7737 |
| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-28937c7ec436426a8e99b95a9912d5742025-01-24T13:23:20ZengMDPI AGBiology2079-77372025-01-011412510.3390/biology14010025Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant GenesWei Dai0Haicong Zhu1Junhong Chen2Hui Chen3Dingzhen Dai4Jian Wu5School of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 210038, ChinaSchool of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 210038, ChinaSchool of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 210038, ChinaSchool of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 210038, ChinaSchool of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing 210038, ChinaDepartment of Bioinformatics, Nanjing Medical University, Nanjing 211166, ChinaBackground: Antibiotics were extensively used in the pigeon breeding industry previously to promote growth and prevent disease, leading to the spread of antibiotic-resistant genes (ARGs) in gut microbes, which has become a major public health concern. Methods: A metagenomic analysis was performed to investigate the gut microbial communities and ARGs in young and older pigeons in Nanjing, Jiangsu Province, China. Results: There were obviously distinct gut microbiota and functional compositions between young and older pigeons. Both Pseudomonadota and Uroviricota were dominant in young and older pigeons. Although sharing 24 gut microbiota phyla between young and older pigeons, Bacillota and Pseudomonadota were the dominant microbial phyla in them, respectively. Besides the shared metabolic pathways and biosynthesis of secondary metabolites, biosynthesis of amino acids was the most abundant Kyoto Encyclopedia of Genes and Genomes (KEGG) function in young pigeons, while microbial metabolism in diverse environments was abundant in older pigeons. A total of 142 ARGs conferring multidrug resistance, tetracycline, and aminoglycoside resistance were identified; the most abundant gene in young pigeons was tetracycline-tetW, while in older pigeons, it was multidrug-acrB. Conclusions: Our findings revealed significant differences in the gut microbial communities and ARGs between young and older pigeons. This study enhances our understanding of pigeon gut microbiota and antibiotic resistomes, contributing to knowledge-based sustainable pigeon meat production.https://www.mdpi.com/2079-7737/14/1/25pigeonmetagenomicsgut microbiotaantibiotic-resistant genes |
| spellingShingle | Wei Dai Haicong Zhu Junhong Chen Hui Chen Dingzhen Dai Jian Wu Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes Biology pigeon metagenomics gut microbiota antibiotic-resistant genes |
| title | Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes |
| title_full | Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes |
| title_fullStr | Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes |
| title_full_unstemmed | Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes |
| title_short | Metagenomic Insights into Pigeon Gut Microbiota Characteristics and Antibiotic-Resistant Genes |
| title_sort | metagenomic insights into pigeon gut microbiota characteristics and antibiotic resistant genes |
| topic | pigeon metagenomics gut microbiota antibiotic-resistant genes |
| url | https://www.mdpi.com/2079-7737/14/1/25 |
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