Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years
Little is known on long-term outcomes in kidney transplantation. This study evaluated changes and predictors of generic and transplantation-specific health-related quality of life (HQoL) over six years in N=102 kidney transplant survivors using the Short-form Health Survey-36 and the Transplant Effe...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2011/671571 |
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| _version_ | 1832561823454330880 |
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| author | Konstadina Griva Jan Stygall Juan Hui Ng Andrew Davenport Mike J. Harrison Stanton Newman |
| author_facet | Konstadina Griva Jan Stygall Juan Hui Ng Andrew Davenport Mike J. Harrison Stanton Newman |
| author_sort | Konstadina Griva |
| collection | DOAJ |
| description | Little is known on long-term outcomes in kidney transplantation. This study evaluated changes and predictors of generic and transplantation-specific health-related quality of life (HQoL) over six years in N=102 kidney transplant survivors using the Short-form Health Survey-36 and the Transplant Effects questionnaire. Mixed models analysis was used to determine long-term outcomes. Emotional HQoL improved over time: Mental Component score, Mental Health, Energy (Ps=.000). Physical HQoL deteriorated: Physical Component Score (P=.001), Pain (P=.002). LRD transplant recipients had greater decline in physical functioning (P=.003) and PCS (P=.000) compared to cadaver recipients. Worry about the transplant (P=.036) and feelings of responsibility (P=.008) increased significantly over time. Worry about the transplant and perceived ability to work predicted 12.7% and 31.1% in variance in MCS and PCS, respectively. Efforts should be made to maintain HQoL and emotional outcomes with ongoing monitoring and support programs throughout the course of posttransplant care. |
| format | Article |
| id | doaj-art-2883139177e34aed98cef11cae76964b |
| institution | Kabale University |
| issn | 2090-0007 2090-0015 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Transplantation |
| spelling | doaj-art-2883139177e34aed98cef11cae76964b2025-02-03T01:24:00ZengWileyJournal of Transplantation2090-00072090-00152011-01-01201110.1155/2011/671571671571Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 YearsKonstadina Griva0Jan Stygall1Juan Hui Ng2Andrew Davenport3Mike J. Harrison4Stanton Newman5Department of Psychology, National University of Singapore, 9Arts Link AS402/28, SingaporeHealth Services Research Group, City University, London, College Building Room A224, St John Street, London EC1V 0HB, UKDepartment of Psychology, National University of Singapore, 9Arts Link AS402/28, SingaporeDepartment of Nephrology, University College, London, and Royal Free Hospital, Pond Street, London NW3 2QG, UKDepartment of Psychology, National University of Singapore, 9Arts Link AS402/28, SingaporeUnit of Behavioural Medicine, University College London, Riding House Street, London W1 8AA, UKLittle is known on long-term outcomes in kidney transplantation. This study evaluated changes and predictors of generic and transplantation-specific health-related quality of life (HQoL) over six years in N=102 kidney transplant survivors using the Short-form Health Survey-36 and the Transplant Effects questionnaire. Mixed models analysis was used to determine long-term outcomes. Emotional HQoL improved over time: Mental Component score, Mental Health, Energy (Ps=.000). Physical HQoL deteriorated: Physical Component Score (P=.001), Pain (P=.002). LRD transplant recipients had greater decline in physical functioning (P=.003) and PCS (P=.000) compared to cadaver recipients. Worry about the transplant (P=.036) and feelings of responsibility (P=.008) increased significantly over time. Worry about the transplant and perceived ability to work predicted 12.7% and 31.1% in variance in MCS and PCS, respectively. Efforts should be made to maintain HQoL and emotional outcomes with ongoing monitoring and support programs throughout the course of posttransplant care.http://dx.doi.org/10.1155/2011/671571 |
| spellingShingle | Konstadina Griva Jan Stygall Juan Hui Ng Andrew Davenport Mike J. Harrison Stanton Newman Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years Journal of Transplantation |
| title | Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years |
| title_full | Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years |
| title_fullStr | Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years |
| title_full_unstemmed | Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years |
| title_short | Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years |
| title_sort | prospective changes in health related quality of life and emotional outcomes in kidney transplantation over 6 years |
| url | http://dx.doi.org/10.1155/2011/671571 |
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