Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report
This case report describes a rare presentation of gastrointestinal stromal tumor (GIST) causing mechanical small bowel obstruction in a 30-year-old female patient with a history of hepatitis B. Initial misdiagnosis as gastritis led to delayed recognition of the underlying pathology. Emergency laparo...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2024-07-01
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| Series: | Caucasian Medical Journal |
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| Online Access: | https://caucasianmedj.com/articles/uncommon-presentation-of-stromal-tumor-causing-small-bowel-obstruction-a-case-report/doi/cmj.galenos.2024.54254 |
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| author | Zamin Adigozalli Rasim Khalilov Steffen Seyfried |
| author_facet | Zamin Adigozalli Rasim Khalilov Steffen Seyfried |
| author_sort | Zamin Adigozalli |
| collection | DOAJ |
| description | This case report describes a rare presentation of gastrointestinal stromal tumor (GIST) causing mechanical small bowel obstruction in a 30-year-old female patient with a history of hepatitis B. Initial misdiagnosis as gastritis led to delayed recognition of the underlying pathology. Emergency laparoscopic intervention revealed mixed epithelioid and spindle cell GIST with high risk features, prompting segmental small bowel resection. Histopathological examination confirmed a PDGFRA mutation, loss of c-kit and DOG 1 expression, and a high mitotic rate, categorizing the tumor as high risk. This case highlights the importance of considering GIST in the differential diagnosis of abdominal symptoms and emphasizes the need for timely intervention to prevent complications. |
| format | Article |
| id | doaj-art-287fa5fbbb2d4faa8f32124da89a1f5e |
| institution | Kabale University |
| issn | 2980-1818 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Caucasian Medical Journal |
| spelling | doaj-art-287fa5fbbb2d4faa8f32124da89a1f5e2025-01-20T07:35:22ZengGalenos Publishing HouseCaucasian Medical Journal2980-18182024-07-0122323310.4274/cmj.galenos.2024.54254Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case ReportZamin Adigozalli0https://orcid.org/0009-0000-2143-2636Rasim Khalilov1https://orcid.org/0009-0003-9514-5164Steffen Seyfried2https://orcid.org/0000-0003-3239-6727Azerbaijan Medical University Baku, AzerbaijanHeidelberg University Surgical Department at the University Medical Centre Mannheim, Mannheim, GermanyHeidelberg University Surgical Department at the University Medical Centre Mannheim, Mannheim, GermanyThis case report describes a rare presentation of gastrointestinal stromal tumor (GIST) causing mechanical small bowel obstruction in a 30-year-old female patient with a history of hepatitis B. Initial misdiagnosis as gastritis led to delayed recognition of the underlying pathology. Emergency laparoscopic intervention revealed mixed epithelioid and spindle cell GIST with high risk features, prompting segmental small bowel resection. Histopathological examination confirmed a PDGFRA mutation, loss of c-kit and DOG 1 expression, and a high mitotic rate, categorizing the tumor as high risk. This case highlights the importance of considering GIST in the differential diagnosis of abdominal symptoms and emphasizes the need for timely intervention to prevent complications.https://caucasianmedj.com/articles/uncommon-presentation-of-stromal-tumor-causing-small-bowel-obstruction-a-case-report/doi/cmj.galenos.2024.54254gastrointestinal stromal tumorsmall bowel obstructionhepatitis blaparoscopyhistopathologyimatinib |
| spellingShingle | Zamin Adigozalli Rasim Khalilov Steffen Seyfried Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report Caucasian Medical Journal gastrointestinal stromal tumor small bowel obstruction hepatitis b laparoscopy histopathology imatinib |
| title | Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report |
| title_full | Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report |
| title_fullStr | Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report |
| title_full_unstemmed | Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report |
| title_short | Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report |
| title_sort | uncommon presentation of stromal tumor causing small bowel obstruction a case report |
| topic | gastrointestinal stromal tumor small bowel obstruction hepatitis b laparoscopy histopathology imatinib |
| url | https://caucasianmedj.com/articles/uncommon-presentation-of-stromal-tumor-causing-small-bowel-obstruction-a-case-report/doi/cmj.galenos.2024.54254 |
| work_keys_str_mv | AT zaminadigozalli uncommonpresentationofstromaltumorcausingsmallbowelobstructionacasereport AT rasimkhalilov uncommonpresentationofstromaltumorcausingsmallbowelobstructionacasereport AT steffenseyfried uncommonpresentationofstromaltumorcausingsmallbowelobstructionacasereport |