Clinical correlations of serum anti-dsDNA immunoglobulin subfamilies in patients with systemic lupus erythematosus (SLE)

Clinical correlations of serum anti-dsDNA immunoglobulin subfamilies in patients with systemic lupus erythematosus (SLE)

Systemic lupus erythematosus (SLE) is an extremely heterogenous autoimmune disorder. A key biomarker, the double stranded (ds) DNA autoantibody, provides diagnostic specificity for SLE. We analyzed anti-dsDNA by mass spectrometry (MS) to determine if ascertaining the autoantibody’s heavy chain varia...

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Bibliographic Details
Main Authors: Jing Jing Wang, Ming Wei Lin, Dan Suan, Dimitra Beroukas, Tom P. Gordon, Adrian Y. S. Lee
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Autoimmunity
Subjects:
Autoantibody
DNA
double-stranded DNA
lupus
mass spectrometry
systemic lupus erythematosus
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2441992
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