ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography

The case illustrates the possible link between coronary spasms, intraluminal thrombus formation, and widespread organized and layered thrombi in HTx patients. Furthermore, the case underlines the clinical value of OCT as a novel method for high-resolution vessel imaging in heart-transplanted (HTx) p...

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Main Authors: Tor Skibsted Clemmensen, Niels Ramsing Holm, Hans Eiskjær, Steen Hvitfeldt Poulsen, Michael Maeng, Christian Juhl Terkelsen, Evald Høj Christiansen
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2016/1863869
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author Tor Skibsted Clemmensen
Niels Ramsing Holm
Hans Eiskjær
Steen Hvitfeldt Poulsen
Michael Maeng
Christian Juhl Terkelsen
Evald Høj Christiansen
author_facet Tor Skibsted Clemmensen
Niels Ramsing Holm
Hans Eiskjær
Steen Hvitfeldt Poulsen
Michael Maeng
Christian Juhl Terkelsen
Evald Høj Christiansen
author_sort Tor Skibsted Clemmensen
collection DOAJ
description The case illustrates the possible link between coronary spasms, intraluminal thrombus formation, and widespread organized and layered thrombi in HTx patients. Furthermore, the case underlines the clinical value of OCT as a novel method for high-resolution vessel imaging in heart-transplanted (HTx) patients with coronary spasms and suspected coronary artery disease. Coronary spasms and sudden death are frequent complications after HTx. The underlying mechanisms leading to these complications are unknown. The present case displays the clinical course of a 19-year-old HTx patient who was hospitalized due to acute myocardial infarction induced by severe coronary spasms. The patients remained unstable on conservative therapy. Therefore, an optical coherence tomography (OCT) was performed and revealed massive, organized thrombi in the left main coronary artery, the circumflex coronary artery, and the left anterior descending coronary artery. The patient was stabilized after percutaneous coronary intervention. As a mural thrombus often goes undetected by coronary angiography, OCT may prove benefit in HTx patients with myocardial infarction or suspected coronary spasms.
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institution Kabale University
issn 2090-6943
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language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Case Reports in Transplantation
spelling doaj-art-2865e230433c46b8acd0d081793eba702025-02-03T01:23:05ZengWileyCase Reports in Transplantation2090-69432090-69512016-01-01201610.1155/2016/18638691863869ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence TomographyTor Skibsted Clemmensen0Niels Ramsing Holm1Hans Eiskjær2Steen Hvitfeldt Poulsen3Michael Maeng4Christian Juhl Terkelsen5Evald Høj Christiansen6Department of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkThe case illustrates the possible link between coronary spasms, intraluminal thrombus formation, and widespread organized and layered thrombi in HTx patients. Furthermore, the case underlines the clinical value of OCT as a novel method for high-resolution vessel imaging in heart-transplanted (HTx) patients with coronary spasms and suspected coronary artery disease. Coronary spasms and sudden death are frequent complications after HTx. The underlying mechanisms leading to these complications are unknown. The present case displays the clinical course of a 19-year-old HTx patient who was hospitalized due to acute myocardial infarction induced by severe coronary spasms. The patients remained unstable on conservative therapy. Therefore, an optical coherence tomography (OCT) was performed and revealed massive, organized thrombi in the left main coronary artery, the circumflex coronary artery, and the left anterior descending coronary artery. The patient was stabilized after percutaneous coronary intervention. As a mural thrombus often goes undetected by coronary angiography, OCT may prove benefit in HTx patients with myocardial infarction or suspected coronary spasms.http://dx.doi.org/10.1155/2016/1863869
spellingShingle Tor Skibsted Clemmensen
Niels Ramsing Holm
Hans Eiskjær
Steen Hvitfeldt Poulsen
Michael Maeng
Christian Juhl Terkelsen
Evald Høj Christiansen
ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
Case Reports in Transplantation
title ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
title_full ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
title_fullStr ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
title_full_unstemmed ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
title_short ST Elevation Infarction after Heart Transplantation Induced by Coronary Spasms and Mural Thrombus Detected by Optical Coherence Tomography
title_sort st elevation infarction after heart transplantation induced by coronary spasms and mural thrombus detected by optical coherence tomography
url http://dx.doi.org/10.1155/2016/1863869
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