Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties
Kaempferia galanga L. (K. galanga) locally called aromatic ginger or “kencur" in Bahasa is traditionally for the treatment of various diseases related to antioxidants such as anti-inflammatory, anti-cancer, and immunomodulator. This paper aims to provide a critical review of the current antioxi...
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LPPT Universitas Gadjah Mada
2024-04-01
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Series: | Journal of Food and Pharmaceutical Sciences |
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Online Access: | https://jurnal.ugm.ac.id/v3/JFPS/article/view/9997/4128 |
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author | Anami Riastri |
author_facet | Anami Riastri |
author_sort | Anami Riastri |
collection | DOAJ |
description | Kaempferia galanga L. (K. galanga) locally called aromatic ginger or “kencur" in Bahasa is traditionally for the treatment of various diseases related to antioxidants such as anti-inflammatory, anti-cancer, and immunomodulator. This paper aims to provide a critical review of the current antioxidant activity of K. galanga using in vitro and in vivo assays. The information and data of K. galanga were collected from various resources such as Scopus, PubMed, Science Direct, and Google Scholar. The results showed that K. galanga plays a role in defense systems against oxidative stress. Several in vitro assays have been used to measure the antioxidant activity of K. galanga, namely,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reduction of antioxidant power (FRAP), 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Whereas, the parameter in vivo antioxidant assay of K galanga including lifespan, survival life, intracellular reactive oxygen species (ROS) level, malondialdehyde (MDA) level, and antioxidant enzyme activities: superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). Based on the findings, it can be indicated that K. galanga has powerful antioxidant activities and, therefore could have the potential as a natural antioxidant. |
format | Article |
id | doaj-art-286530ce2c4b43258f123978663e4a5e |
institution | Kabale University |
issn | 2089-7200 2339-0948 |
language | English |
publishDate | 2024-04-01 |
publisher | LPPT Universitas Gadjah Mada |
record_format | Article |
series | Journal of Food and Pharmaceutical Sciences |
spelling | doaj-art-286530ce2c4b43258f123978663e4a5e2025-01-24T08:49:49ZengLPPT Universitas Gadjah MadaJournal of Food and Pharmaceutical Sciences2089-72002339-09482024-04-01121677910.22146/jfps.9997Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant PropertiesAnami Riastri0Department of Pharmacy, Faculty of Mathematics and Sciences, Universitas Islam Indonesia, Yogyakarta, 55584, IndonesiaKaempferia galanga L. (K. galanga) locally called aromatic ginger or “kencur" in Bahasa is traditionally for the treatment of various diseases related to antioxidants such as anti-inflammatory, anti-cancer, and immunomodulator. This paper aims to provide a critical review of the current antioxidant activity of K. galanga using in vitro and in vivo assays. The information and data of K. galanga were collected from various resources such as Scopus, PubMed, Science Direct, and Google Scholar. The results showed that K. galanga plays a role in defense systems against oxidative stress. Several in vitro assays have been used to measure the antioxidant activity of K. galanga, namely,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reduction of antioxidant power (FRAP), 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Whereas, the parameter in vivo antioxidant assay of K galanga including lifespan, survival life, intracellular reactive oxygen species (ROS) level, malondialdehyde (MDA) level, and antioxidant enzyme activities: superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). Based on the findings, it can be indicated that K. galanga has powerful antioxidant activities and, therefore could have the potential as a natural antioxidant.https://jurnal.ugm.ac.id/v3/JFPS/article/view/9997/4128antioxidantkaempferia galanga (l.)in vitroin vivooxidative stress |
spellingShingle | Anami Riastri Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties Journal of Food and Pharmaceutical Sciences antioxidant kaempferia galanga (l.) in vitro in vivo oxidative stress |
title | Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties |
title_full | Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties |
title_fullStr | Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties |
title_full_unstemmed | Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties |
title_short | Kaempferia galanga (L.): An Updated Overview of In Vitro and In Vivo Antioxidant Properties |
title_sort | kaempferia galanga l an updated overview of in vitro and in vivo antioxidant properties |
topic | antioxidant kaempferia galanga (l.) in vitro in vivo oxidative stress |
url | https://jurnal.ugm.ac.id/v3/JFPS/article/view/9997/4128 |
work_keys_str_mv | AT anamiriastri kaempferiagalangalanupdatedoverviewofinvitroandinvivoantioxidantproperties |