Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies

Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies

Effective cancer therapies must address the tumor microenvironment (TME), a complex network of tumor cells and stromal components, including endothelial, immune, and mesenchymal cells. Durable outcomes require targeting both tumor cells and the TME while minimizing systemic toxicity. Interleukin-2 (...

Full description

Saved in:
Bibliographic Details
Main Authors: Sahar Balkhi, Giorgia Bilato, Andrea De Lerma Barbaro, Paola Orecchia, Alessandro Poggi, Lorenzo Mortara
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
IL-2
immunotoxins
immunocytokines
Online Access:https://www.mdpi.com/2076-393X/13/1/69
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items