Research advances of miRNA in the pathogenesis of diabetic kidney disease
As one of the microvascular complications caused by diabetes mellitus, diabetic kidney disease（DKD）is a major cause for shorter life expectancy of diabetes mellitus（DM）patients.It has been known that the pathogenesis of DKD is correlated with an accumulation of extracellular matrix, oxidative stress...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2021-01-01
|
| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57905460&Fpath=home&index=0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849323467399233536 |
|---|---|
| author | Duan Ying-lian Ma Chan-juan |
| author_facet | Duan Ying-lian Ma Chan-juan |
| author_sort | Duan Ying-lian |
| collection | DOAJ |
| description | As one of the microvascular complications caused by diabetes mellitus, diabetic kidney disease（DKD）is a major cause for shorter life expectancy of diabetes mellitus（DM）patients.It has been known that the pathogenesis of DKD is correlated with an accumulation of extracellular matrix, oxidative stress, inflammatory response and autophagy.And miRNA remains quite stable and it may be detected in human fluids.As a promising biomarker for kidneys, it has provided supplements for testing indicators of kidney disease.A better understanding the regulatory role of miRNAs in the pathogenesis of DKD shall be vital in the diagnosis and treatment of DKD.This review focused upon the correlation between miRNAs and the pathogenesis of DKD. |
| format | Article |
| id | doaj-art-27f381b561464febba4b20510d4a45d8 |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2021-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-27f381b561464febba4b20510d4a45d82025-08-20T03:49:02ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0124324857905460Research advances of miRNA in the pathogenesis of diabetic kidney diseaseDuan Ying-lianMa Chan-juanAs one of the microvascular complications caused by diabetes mellitus, diabetic kidney disease（DKD）is a major cause for shorter life expectancy of diabetes mellitus（DM）patients.It has been known that the pathogenesis of DKD is correlated with an accumulation of extracellular matrix, oxidative stress, inflammatory response and autophagy.And miRNA remains quite stable and it may be detected in human fluids.As a promising biomarker for kidneys, it has provided supplements for testing indicators of kidney disease.A better understanding the regulatory role of miRNAs in the pathogenesis of DKD shall be vital in the diagnosis and treatment of DKD.This review focused upon the correlation between miRNAs and the pathogenesis of DKD.http://www.lcszb.com/thesisDetails?columnId=57905460&Fpath=home&index=0Diabetic kidney diseaseMiRNAPathogenesis |
| spellingShingle | Duan Ying-lian Ma Chan-juan Research advances of miRNA in the pathogenesis of diabetic kidney disease Linchuang shenzangbing zazhi Diabetic kidney disease MiRNA Pathogenesis |
| title | Research advances of miRNA in the pathogenesis of diabetic kidney disease |
| title_full | Research advances of miRNA in the pathogenesis of diabetic kidney disease |
| title_fullStr | Research advances of miRNA in the pathogenesis of diabetic kidney disease |
| title_full_unstemmed | Research advances of miRNA in the pathogenesis of diabetic kidney disease |
| title_short | Research advances of miRNA in the pathogenesis of diabetic kidney disease |
| title_sort | research advances of mirna in the pathogenesis of diabetic kidney disease |
| topic | Diabetic kidney disease MiRNA Pathogenesis |
| url | http://www.lcszb.com/thesisDetails?columnId=57905460&Fpath=home&index=0 |
| work_keys_str_mv | AT duanyinglian researchadvancesofmirnainthepathogenesisofdiabetickidneydisease AT machanjuan researchadvancesofmirnainthepathogenesisofdiabetickidneydisease |