Parameter estimation in a structured erythropoiesis model
We develop a numerical method for estimating parameters in astructured erythropoiesis model consisting of a nonlinear system ofpartial differential equations. Convergence theory for the computedparameters is provided. Numerical results for estimating the growthrate of precursor cells as a function o...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2008-09-01
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| Series: | Mathematical Biosciences and Engineering |
| Subjects: | |
| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.601 |
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| Summary: | We develop a numerical method for estimating parameters in astructured erythropoiesis model consisting of a nonlinear system ofpartial differential equations. Convergence theory for the computedparameters is provided. Numerical results for estimating the growthrate of precursor cells as a function of the erythropoietinconcentration and the decay rate of erythropoietin as a function ofthe total number of precursor cells from computationally generateddata are provided. Standard errors for such parameters are alsogiven. |
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| ISSN: | 1551-0018 |