Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study
<b>Background</b>: Progressive supranuclear palsy (PSP) is characterized by early postural instability and gait dysfunction, with frequent falls. Rehabilitation is an important therapeutic approach for motor dysfunction in patients with PSP. However, no conclusions have yet been drawn re...
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2025-01-01
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| author | Naomi Matsuda Yasuyuki Takamatsu Makoto Sawada Ikuko Aiba |
| author_facet | Naomi Matsuda Yasuyuki Takamatsu Makoto Sawada Ikuko Aiba |
| author_sort | Naomi Matsuda |
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| description | <b>Background</b>: Progressive supranuclear palsy (PSP) is characterized by early postural instability and gait dysfunction, with frequent falls. Rehabilitation is an important therapeutic approach for motor dysfunction in patients with PSP. However, no conclusions have yet been drawn regarding the beneficial effects of rehabilitation in PSP, including the optimal duration of rehabilitation and differences in treatment effects among PSP subtypes. Herein, we investigated the effects of short-term rehabilitation and separately analyzed the effects on patients with PSP-Richardson’s syndrome (RS) and PSP-progressive gait freezing (PGF). <b>Methods</b>: The participants underwent several therapeutic exercise programs individualized for each participant, performed over 2 weeks. Analysis was performed on 25 patients with PSP-RS and eight with PSP-PGF. <b>Results</b>: Short-term rehabilitation improved the Berg Balance Scale score in both the PSP-RS and PSP-PGF groups, step length on the symptom-dominant side in PSP-RS, the coefficient of variation of step length on the symptom-dominant side, and the stance phase of the Symmetry Index in PSP-PGF. <b>Conclusions</b>: Overall, this 2-week short-term rehabilitation intervention was shown to have beneficial effects on balance in patients with PSP-RS and PSP-PGF. |
| format | Article |
| id | doaj-art-27aefabaca824afb96e151dff996949b |
| institution | Kabale University |
| issn | 2076-3425 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj-art-27aefabaca824afb96e151dff996949b2025-01-24T13:25:56ZengMDPI AGBrain Sciences2076-34252025-01-011518810.3390/brainsci15010088Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post StudyNaomi Matsuda0Yasuyuki Takamatsu1Makoto Sawada2Ikuko Aiba3Department of Rehabilitation, NHO Higashinagoya National Hospital, Nagoya 465-8620, JapanDepartment of Physical Therapy, College of Life and Health Sciences, Chubu University, Kasugai 487-8501, JapanSchool of Physical Therapy, Faculty of Rehabilitation, Reiwa Health Sciences University, Fukuoka 811-0213, JapanDepartment of Neurology, NHO Higashinagoya National Hospital, Nagoya 465-8620, Japan<b>Background</b>: Progressive supranuclear palsy (PSP) is characterized by early postural instability and gait dysfunction, with frequent falls. Rehabilitation is an important therapeutic approach for motor dysfunction in patients with PSP. However, no conclusions have yet been drawn regarding the beneficial effects of rehabilitation in PSP, including the optimal duration of rehabilitation and differences in treatment effects among PSP subtypes. Herein, we investigated the effects of short-term rehabilitation and separately analyzed the effects on patients with PSP-Richardson’s syndrome (RS) and PSP-progressive gait freezing (PGF). <b>Methods</b>: The participants underwent several therapeutic exercise programs individualized for each participant, performed over 2 weeks. Analysis was performed on 25 patients with PSP-RS and eight with PSP-PGF. <b>Results</b>: Short-term rehabilitation improved the Berg Balance Scale score in both the PSP-RS and PSP-PGF groups, step length on the symptom-dominant side in PSP-RS, the coefficient of variation of step length on the symptom-dominant side, and the stance phase of the Symmetry Index in PSP-PGF. <b>Conclusions</b>: Overall, this 2-week short-term rehabilitation intervention was shown to have beneficial effects on balance in patients with PSP-RS and PSP-PGF.https://www.mdpi.com/2076-3425/15/1/88progressive supranuclear palsyRichardson’s syndromeprogressive gait freezingrehabilitationshort-termbalance |
| spellingShingle | Naomi Matsuda Yasuyuki Takamatsu Makoto Sawada Ikuko Aiba Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study Brain Sciences progressive supranuclear palsy Richardson’s syndrome progressive gait freezing rehabilitation short-term balance |
| title | Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study |
| title_full | Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study |
| title_fullStr | Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study |
| title_full_unstemmed | Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study |
| title_short | Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study |
| title_sort | performance of a two week rehabilitation improves motor function in inpatients with progressive supranuclear palsy a pre post study |
| topic | progressive supranuclear palsy Richardson’s syndrome progressive gait freezing rehabilitation short-term balance |
| url | https://www.mdpi.com/2076-3425/15/1/88 |
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