Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma

Multiple myeloma, a plasma cell neoplasm, presents most commonly with anemia, hypercalcemia, renal failure, and bone pain. Only few cases of clinical aggressive presentation associated with bleeding were reported in the medical literature. The reported cases included gastrointestinal bleeding and ca...

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Main Authors: Aydah Alawadhi, Laszlo Leb
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2016/8206826
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author Aydah Alawadhi
Laszlo Leb
author_facet Aydah Alawadhi
Laszlo Leb
author_sort Aydah Alawadhi
collection DOAJ
description Multiple myeloma, a plasma cell neoplasm, presents most commonly with anemia, hypercalcemia, renal failure, and bone pain. Only few cases of clinical aggressive presentation associated with bleeding were reported in the medical literature. The reported cases included gastrointestinal bleeding and cardiac tamponade. Spontaneous retroperitoneal haemorrhage as initial presentation has not been so far reported. We hereby report a case of a 64-year-old female who was found to have catastrophic hemorrhage in the retroperitoneal region that extended into intrathecal space causing cord compression. The case posed a significant diagnostic and management dilemma. This case emphasizes the need to think broadly and include multiple myeloma in the diagnosis of unexplained massive retroperitoneal bleeding.
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institution Kabale University
issn 2090-6560
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series Case Reports in Hematology
spelling doaj-art-27a691090fbe4a33bbcc9920054ac66a2025-02-03T01:09:23ZengWileyCase Reports in Hematology2090-65602090-65792016-01-01201610.1155/2016/82068268206826Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple MyelomaAydah Alawadhi0Laszlo Leb1Department of Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA 01608, USADepartment of Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA 01608, USAMultiple myeloma, a plasma cell neoplasm, presents most commonly with anemia, hypercalcemia, renal failure, and bone pain. Only few cases of clinical aggressive presentation associated with bleeding were reported in the medical literature. The reported cases included gastrointestinal bleeding and cardiac tamponade. Spontaneous retroperitoneal haemorrhage as initial presentation has not been so far reported. We hereby report a case of a 64-year-old female who was found to have catastrophic hemorrhage in the retroperitoneal region that extended into intrathecal space causing cord compression. The case posed a significant diagnostic and management dilemma. This case emphasizes the need to think broadly and include multiple myeloma in the diagnosis of unexplained massive retroperitoneal bleeding.http://dx.doi.org/10.1155/2016/8206826
spellingShingle Aydah Alawadhi
Laszlo Leb
Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma
Case Reports in Hematology
title Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma
title_full Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma
title_fullStr Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma
title_full_unstemmed Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma
title_short Massive Retroperitoneal Hemorrhage as an Initial Presentation of a Rare and Aggressive Form of Multiple Myeloma
title_sort massive retroperitoneal hemorrhage as an initial presentation of a rare and aggressive form of multiple myeloma
url http://dx.doi.org/10.1155/2016/8206826
work_keys_str_mv AT aydahalawadhi massiveretroperitonealhemorrhageasaninitialpresentationofarareandaggressiveformofmultiplemyeloma
AT laszloleb massiveretroperitonealhemorrhageasaninitialpresentationofarareandaggressiveformofmultiplemyeloma