Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors
To learn the differences between the structure-activity relationship and molecular vibration-activity relationship in the ligand-receptor interaction of the histamine receptor, 47 ligands of the histamine receptor were analyzed by structural similarity and molecular vibrational frequency patterns. T...
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| Format: | Article |
| Language: | English |
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BioMed Central
2012-06-01
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| Series: | Genomics & Informatics |
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| Online Access: | http://genominfo.org/upload/pdf/gni-10-128.pdf |
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| author | S. June Oh |
| author_facet | S. June Oh |
| author_sort | S. June Oh |
| collection | DOAJ |
| description | To learn the differences between the structure-activity relationship and molecular vibration-activity relationship in the ligand-receptor interaction of the histamine receptor, 47 ligands of the histamine receptor were analyzed by structural similarity and molecular vibrational frequency patterns. The radial tree that was produced by clustering analysis of molecular vibrational frequency patterns shows its potential for the functional classification of histamine receptor ligands. |
| format | Article |
| id | doaj-art-279a2212e25c40eca4447cae03a61a16 |
| institution | Kabale University |
| issn | 1598-866X 2234-0742 |
| language | English |
| publishDate | 2012-06-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-279a2212e25c40eca4447cae03a61a162025-02-02T05:44:14ZengBioMed CentralGenomics & Informatics1598-866X2234-07422012-06-0110212813210.5808/GI.2012.10.2.1286Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine ReceptorsS. June Oh0Department of Pharmacology, Inje University College of Medicine, Busan 614-735, Korea.To learn the differences between the structure-activity relationship and molecular vibration-activity relationship in the ligand-receptor interaction of the histamine receptor, 47 ligands of the histamine receptor were analyzed by structural similarity and molecular vibrational frequency patterns. The radial tree that was produced by clustering analysis of molecular vibrational frequency patterns shows its potential for the functional classification of histamine receptor ligands.http://genominfo.org/upload/pdf/gni-10-128.pdfcorralled intensity of molecular vibrational frequencyG protein-coupled receptorshistamine receptorsmolecular vibration-activity relationship |
| spellingShingle | S. June Oh Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors Genomics & Informatics corralled intensity of molecular vibrational frequency G protein-coupled receptors histamine receptors molecular vibration-activity relationship |
| title | Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors |
| title_full | Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors |
| title_fullStr | Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors |
| title_full_unstemmed | Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors |
| title_short | Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors |
| title_sort | characteristics in molecular vibrational frequency patterns between agonists and antagonists of histamine receptors |
| topic | corralled intensity of molecular vibrational frequency G protein-coupled receptors histamine receptors molecular vibration-activity relationship |
| url | http://genominfo.org/upload/pdf/gni-10-128.pdf |
| work_keys_str_mv | AT sjuneoh characteristicsinmolecularvibrationalfrequencypatternsbetweenagonistsandantagonistsofhistaminereceptors |