Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism

Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponad...

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Main Authors: Moaaz Baghal, Viralkumar Amrutiya, Bhoomi Patel, Rutwik Patel, Jonathan Hernandez, Mohamed Ahmed, Abraham Lo, Mark Gabelman
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2021/2666601
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author Moaaz Baghal
Viralkumar Amrutiya
Bhoomi Patel
Rutwik Patel
Jonathan Hernandez
Mohamed Ahmed
Abraham Lo
Mark Gabelman
author_facet Moaaz Baghal
Viralkumar Amrutiya
Bhoomi Patel
Rutwik Patel
Jonathan Hernandez
Mohamed Ahmed
Abraham Lo
Mark Gabelman
author_sort Moaaz Baghal
collection DOAJ
description Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponade with the finding of elevation of a blood tumor marker, CA-125, in the setting of nonadherence to thyroid replacement therapy. She was managed by surgical pericardial window and abdominal paracentesis, with replacement of thyroid hormones leading to resolution of the tamponade and ascites. CA-125 elevation associated with cardiac tamponade and myxedema ascites due to hypothyroidism is very rare, and we aim to shed light on the importance of having a broad differential when approaching cardiac tamponade and understand the association between CA-125 and hypothyroidism.
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institution Kabale University
issn 2090-6412
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publishDate 2021-01-01
publisher Wiley
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series Case Reports in Cardiology
spelling doaj-art-2790800213ce4670a2bcc90f8bad86802025-02-03T06:06:51ZengWileyCase Reports in Cardiology2090-64122021-01-01202110.1155/2021/2666601Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated HypothyroidismMoaaz Baghal0Viralkumar Amrutiya1Bhoomi Patel2Rutwik Patel3Jonathan Hernandez4Mohamed Ahmed5Abraham Lo6Mark Gabelman7Hackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterHackensack Meridian Health Palisades Medical CenterCardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponade with the finding of elevation of a blood tumor marker, CA-125, in the setting of nonadherence to thyroid replacement therapy. She was managed by surgical pericardial window and abdominal paracentesis, with replacement of thyroid hormones leading to resolution of the tamponade and ascites. CA-125 elevation associated with cardiac tamponade and myxedema ascites due to hypothyroidism is very rare, and we aim to shed light on the importance of having a broad differential when approaching cardiac tamponade and understand the association between CA-125 and hypothyroidism.http://dx.doi.org/10.1155/2021/2666601
spellingShingle Moaaz Baghal
Viralkumar Amrutiya
Bhoomi Patel
Rutwik Patel
Jonathan Hernandez
Mohamed Ahmed
Abraham Lo
Mark Gabelman
Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
Case Reports in Cardiology
title Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_full Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_fullStr Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_full_unstemmed Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_short Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_sort pericardial tamponade and elevated serum ca 125 level in inadequately treated hypothyroidism
url http://dx.doi.org/10.1155/2021/2666601
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AT bhoomipatel pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT rutwikpatel pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT jonathanhernandez pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
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