Vitamin B12 deficiency and cognitive impairment: A comprehensive review of neurological impact

Vitamin B12 deficiency and cognitive impairment: A comprehensive review of neurological impact

Cognitive impairment, a prevalent issue in aging populations, significantly affects quality of life and public health systems. Among various contributing factors, Vitamin B12 deficiency emerges as a critical yet modifiable risk factor, impacting neurological and cognitive health. Vitamin B12, an ess...

Full description

Saved in:

Bibliographic Details
Main Authors:	Milind Umekar, Tanvi Premchandani, Amol Tatode, Mohammad Qutub, Neha Raut, Jayshree Taksande, Ujban Md. Hussain
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Series:	Brain Disorders
Subjects:	Neuroprotection Methylcobalamin Myelin degeneration Homocysteine Neurodegeneration Environmental stressors
Online Access:	http://www.sciencedirect.com/science/article/pii/S266645932500040X
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Engineered Exosomes as Smart Drug Carriers: Overcoming Biological Barriers in CNS and Cancer Therapy
by: Tanvi Premchandani, et al.
Published: (2025-04-01)

Deciphering the Structural and Functional Paradigms of <i>Clostridioides difficile</i> Toxins TcdA and TcdB
by: Mohammad Qutub, et al.
Published: (2025-04-01)

Faecal microbiota transplantation as a novel approach for autism-associated anxiety: A critical therapeutic appraisal
by: Tanushree D. Malode, et al.
Published: (2025-09-01)

Cobalamin deficiency and pathogenesis of neurological disorders
by: A. V. Pereshein, et al.
Published: (2021-12-01)

Evaluation of a New Sublingual Methylcobalamin Dosage Regimen for Childhood Vitamin B12 Deficiency
by: Sultan Aydin, et al.
Published: (2025-03-01)

Overview of homocysteine and its role in disease processes
by: Aleksandra Kędzia, et al.
Published: (2025-05-01)

The Impacts of Dietary Intervention on Brain Metabolism and Neurological Disorders: A Narrative Review
by: Priya Rathor, et al.
Published: (2024-08-01)

Human Schwann Cell-Derived Extracellular Vesicle Isolation, Bioactivity Assessment, and Omics Characterization
by: Khan A, et al.
Published: (2025-04-01)

Oxidative stress and inflammation in the pathogenesis of neurological disorders: Mechanisms and implications
by: Umesh Chandra Dash, et al.
Published: (2025-01-01)

Modulation of miR-145 in a mouse model of multiple sclerosis: A promising approach to attenuate inflammation and degeneration
by: Monique Marylin Alves de Almeida, et al.
Published: (2025-09-01)

Green and white analytical approach for parallel quantification of gabapentin and methylcobalamin in medicinal products using inventive RP-HPLC technique
by: Samar M. Mahgoub, et al.
Published: (2025-06-01)

Conical Chitosan Conduits Combined With Methylcobalamin for Sciatic Nerve Transposition Repair
by: Qicheng Li, et al.
Published: (2025-06-01)

Serum homocysteine levels predict poor recovery and relapse in first-attack myelin oligodendrocyte glycoprotein antibody disease
by: Yanfei Li, et al.
Published: (2025-07-01)

Wallerian degeneration: From mechanism to disease to imaging
by: Ruiqi Tian, et al.
Published: (2025-01-01)

From Molecules to Mind: The Critical Role of Chitosan, Collagen, Alginate, and Other Biopolymers in Neuroprotection and Neurodegeneration
by: Weronika Kruczkowska, et al.
Published: (2025-02-01)

Exercise-Induced Neuroplasticity: Adaptive Mechanisms and Preventive Potential in Neurodegenerative Disorders
by: Masab Mansoor, et al.
Published: (2025-04-01)

Therapeutic implications of necroptosis activation in Alzheimer´s disease
by: Elizabeth Carrazana, et al.
Published: (2024-12-01)

Editorial: 15 years of Frontiers in Cellular Neuroscience: the dual role of microglia in (neuro)inflammation
by: Antonio J. Herrera, et al.
Published: (2025-02-01)

Dapagliflozin combined with methylcobalamin in the treatment of type 2 diabetes mellitus with peripheral neuropathy: a systematic review and meta-analysis
by: Xiao-Long Deng, et al.
Published: (2025-06-01)

Nootropic foods in neurodegenerative diseases: mechanisms, challenges, and future
by: Le Anh Minh Nguyen, et al.
Published: (2025-04-01)

Editorial: 15 years of frontiers in neuroanatomy: the origin of Parkinson's disease
by: Barbara Falquetto, et al.
Published: (2025-07-01)

Correction: Editorial: 15 years of frontiers in neuroanatomy: the origin of Parkinson's disease
by: Barbara Falquetto, et al.
Published: (2025-07-01)

Enhanced therapy for diabetic neuropathy utilizing venlafaxine hydrochloride-loaded transferosome-based transdermal gel
by: Kajol Patil, et al.
Published: (2025-03-01)

Polyphenols, Alkaloids, and Terpenoids Against Neurodegeneration: Evaluating the Neuroprotective Effects of Phytocompounds Through a Comprehensive Review of the Current Evidence
by: Enzo Pereira de Lima, et al.
Published: (2025-02-01)

Neuroprotective Effects of Ascorbic Acid, Vanillic Acid, and Ferulic Acid in Dopaminergic Neurons of Zebrafish
by: Fatemeh Hedayatikatouli, et al.
Published: (2024-10-01)

Inhibition of neuroinflammation by GIBH-130 (AD-16) reduces neurodegeneration, motor deficits, and proinflammatory cytokines in a hemiparkinsonian model
by: Maria E. Bianchetti, et al.
Published: (2024-12-01)

Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma
by: Anne Rombaut, et al.
Published: (2024-11-01)

Estimation of the level of homocysteine and vitamin B12 in serum of patients with hypothyroidism
by: Asala Adnan Otla, et al.
Published: (2019-03-01)

The effect of a specific vitamin supplement containing L-methylfolate (Ocufolin forte) in patients with neovascular age-related macular degeneration
by: Tatjana Josifova, et al.
Published: (2025-05-01)

Interaction of vitamin D, homocystein and dental diseases
by: O.I. Kutelmakh
Published: (2019-03-01)

Oligodendroglial heterogeneity in health, disease, and recovery: deeper insights into myelin dynamics
by: Pieter-Jan Serneels, et al.
Published: (2025-11-01)

In Silico Modeling of Myelin Oligodendrocyte Glycoprotein Disulfide Bond Reduction by Phosphine-Borane Complexes
by: Raheem Remtulla, et al.
Published: (2024-10-01)

Systemic semaglutide provides a mild vasoprotective and antineuroinflammatory effect in a rat model of ocular hypertensive glaucoma
by: Zaynab A. Mouhammad, et al.
Published: (2025-07-01)

Join us on an amazing journey towards next‐generation treatments for CNS disorders: Launch of Neuroprotection, a new high‐quality journal in translational neuroscience
by: Xunming Ji, et al.
Published: (2023-09-01)

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection
by: Md. Rezaul Islam, et al.
Published: (2025-05-01)

Maternal and Cord Blood Vitamin B12, Folate and Homocysteine Levels
by: Selime Özen Bölük, et al.
Published: (2022-06-01)

Regional analysis of myelin basic protein across postnatal brain development of C57BL/6J mice
by: Siddhi S. Ozarkar, et al.
Published: (2025-03-01)

Current Opportunities and Future Prospects of Neuroprotective Therapy in Glaucoma. Literature Review. Part 2
by: N. I. Kurysheva, et al.
Published: (2025-06-01)

Antioxidant and neuroprotective effects of nutriosomes and grape pomace phytochemicals in a cell model of oxidative stress and mouse model of Parkinson disease
by: Mohamad Allaw, et al.
Published: (2025-04-01)

Current Opportunities and Future Prospects of Neuroprotective Therapy in Glaucoma. Literature Review. Part 1
by: N. I. Kurysheva, et al.
Published: (2025-03-01)