Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice

Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice

Abstract Background Hydroxyapatite (HAP) resembles the components of biological hard tissue. Recent research has been interested in the biomedical application of HAP nanoparticles (HAP-NPs) in cancer treatment, HAP-NPs have high cytotoxic activity against cancerous cells, in addition, they are nonto...

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Bibliographic Details
Main Authors: Shaymaa M. Eissa, Asmaa M. Mahfouz, Saad M. El-Gendy, Al-shimaa Zakaria, Heba Effat, Hanan R. H. Mohamed
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Hydroxyapatite
Ehrlich solid carcinoma
Cisplatin
Apoptosis
DNA damage
Online Access:https://doi.org/10.1186/s43088-025-00595-0
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