Zinc Protoporphyrin Upregulates Heme Oxygenase-1 in PC-3 Cells via the Stress Response Pathway

Zinc Protoporphyrin Upregulates Heme Oxygenase-1 in PC-3 Cells via the Stress Response Pathway

Zinc protoporphyrin IX (ZnPP), a naturally occurring molecule formed in iron deficiency or lead poisoning, is a potent competitive inhibitor of heme oxygenase-1 (HO-1). It also regulates expression of HO-1 at the transcriptional level. However, the effect of ZnPP on HO-1 expression is controversial....

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Bibliographic Details
Main Author:	Simon C. M. Kwok
Format:	Article
Language:	English
Published:	Wiley 2013-01-01
Series:	International Journal of Cell Biology
Online Access:	http://dx.doi.org/10.1155/2013/162094
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