Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues

Stem cells can be used to replace damaged cells or regenerate organs and have broadened our knowledge of the development and progression of certain diseases. Despite significant advances in understanding stem cell biology, several problems limit their use. These problems are related not only to the...

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Main Authors: Ioannis Alexandros Charitos, Andrea Ballini, Stefania Cantore, Mariarosaria Boccellino, Marina Di Domenico, Elisa Borsani, Riccardo Nocini, Michele Di Cosola, Luigi Santacroce, Lucrezia Bottalico
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2021/9978837
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author Ioannis Alexandros Charitos
Andrea Ballini
Stefania Cantore
Mariarosaria Boccellino
Marina Di Domenico
Elisa Borsani
Riccardo Nocini
Michele Di Cosola
Luigi Santacroce
Lucrezia Bottalico
author_facet Ioannis Alexandros Charitos
Andrea Ballini
Stefania Cantore
Mariarosaria Boccellino
Marina Di Domenico
Elisa Borsani
Riccardo Nocini
Michele Di Cosola
Luigi Santacroce
Lucrezia Bottalico
author_sort Ioannis Alexandros Charitos
collection DOAJ
description Stem cells can be used to replace damaged cells or regenerate organs and have broadened our knowledge of the development and progression of certain diseases. Despite significant advances in understanding stem cell biology, several problems limit their use. These problems are related not only to the growth of tumors in animal models and their rejection in transplant cases but also to ethical and social issues about the use of embryonic cells. The ethical-scientific debate on this type of cells has taken on great interest both for their application in regenerative medicine and for the potential possibilities in the field of cell and gene therapy. Different points of view often have the expression of a perception that depends on scientific goals or opportunities or on religious traditions and beliefs. Therefore, as the questions and doubts about when life begins, so do the answers for the use of these cells as therapy or otherwise. So, in addition to the origin of stem cells, there are currently some social bioethical (such as political and legislative issues) and religious dilemmas. The purpose of the study is aimed at being a narrative on the history of stem cells and the evolution of their use to date, as well as to clarify the bioethical position of the various religions today in comparison with the social ones regarding the research and use of embryonic and adult ones. Hence, their biological hypostasis regarding the concepts of “conception” and “fertilization” and their development and therapeutic use compared to those of the main theological doctrines.
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institution Kabale University
issn 1687-966X
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series Stem Cells International
spelling doaj-art-2726d33d564b4ad8a40998bbd5a734432025-02-03T01:06:16ZengWileyStem Cells International1687-966X1687-96782021-01-01202110.1155/2021/99788379978837Stem Cells: A Historical Review about Biological, Religious, and Ethical IssuesIoannis Alexandros Charitos0Andrea Ballini1Stefania Cantore2Mariarosaria Boccellino3Marina Di Domenico4Elisa Borsani5Riccardo Nocini6Michele Di Cosola7Luigi Santacroce8Lucrezia Bottalico9Interdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari, Bari, ItalyDepartment of Biosciences, Biotechnologies and Biopharmaceutics, Campus Universitario “Ernesto Quagliariello”, University of Bari “Aldo Moro”, Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari, School of Medicine, Bari, ItalyDepartment of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, ItalyDepartment of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, ItalyDivision of Anatomy and Physiopathology, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, ItalySection of Ear Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynecology and Pediatric, University of Verona, Verona, ItalyDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, ItalyDepartment of Interdisciplinary Medicine, University of Bari, School of Medicine, Bari, ItalyInterdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari, Bari, ItalyStem cells can be used to replace damaged cells or regenerate organs and have broadened our knowledge of the development and progression of certain diseases. Despite significant advances in understanding stem cell biology, several problems limit their use. These problems are related not only to the growth of tumors in animal models and their rejection in transplant cases but also to ethical and social issues about the use of embryonic cells. The ethical-scientific debate on this type of cells has taken on great interest both for their application in regenerative medicine and for the potential possibilities in the field of cell and gene therapy. Different points of view often have the expression of a perception that depends on scientific goals or opportunities or on religious traditions and beliefs. Therefore, as the questions and doubts about when life begins, so do the answers for the use of these cells as therapy or otherwise. So, in addition to the origin of stem cells, there are currently some social bioethical (such as political and legislative issues) and religious dilemmas. The purpose of the study is aimed at being a narrative on the history of stem cells and the evolution of their use to date, as well as to clarify the bioethical position of the various religions today in comparison with the social ones regarding the research and use of embryonic and adult ones. Hence, their biological hypostasis regarding the concepts of “conception” and “fertilization” and their development and therapeutic use compared to those of the main theological doctrines.http://dx.doi.org/10.1155/2021/9978837
spellingShingle Ioannis Alexandros Charitos
Andrea Ballini
Stefania Cantore
Mariarosaria Boccellino
Marina Di Domenico
Elisa Borsani
Riccardo Nocini
Michele Di Cosola
Luigi Santacroce
Lucrezia Bottalico
Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
Stem Cells International
title Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
title_full Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
title_fullStr Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
title_full_unstemmed Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
title_short Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
title_sort stem cells a historical review about biological religious and ethical issues
url http://dx.doi.org/10.1155/2021/9978837
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