Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study
The study aim was to assess sympathetic vasomotor response (SVR) by using pulsed wave Doppler (PWD) ultrasound in patients with multiple system atrophy (MSA) and correlate with the tilt table study. We recruited 18 male patients and 10 healthy men as controls. The SVR of the radial artery was evalua...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/548529 |
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| author | Ke-Vin Chang Wen-Shiang Chen Ruey-Meei Wu Ssu-Yuan Chen Hsiu-Yu Shen Ching Lan Yen-Ho Wang |
| author_facet | Ke-Vin Chang Wen-Shiang Chen Ruey-Meei Wu Ssu-Yuan Chen Hsiu-Yu Shen Ching Lan Yen-Ho Wang |
| author_sort | Ke-Vin Chang |
| collection | DOAJ |
| description | The study aim was to assess sympathetic vasomotor response (SVR) by using pulsed wave Doppler (PWD) ultrasound in patients with multiple system atrophy (MSA) and correlate with the tilt table study. We recruited 18 male patients and 10 healthy men as controls. The SVR of the radial artery was evaluated by PWD, using inspiratory cough as a provocative maneuver. The response to head-up tilt was studied by a tilt table with simultaneous heart rate and blood pressure recording. The hemodynamic variables were compared between groups, and were examined by correlation analysis. Regarding SVR, MSA patients exhibited a prolonged latency and less heart rate acceleration following inspiratory cough. Compared with the tilt table test, the elevation of heart rate upon SVR was positively correlated to the increase of heart rate after head-up tilt. The correlation analysis indicated that the magnitude of blood pressure drop from supine to upright was positively associated with the SVR latency but negatively correlated with the heart rate changes upon SVR. The present study demonstrated that blunted heart rate response might explain MSA's vulnerability to postural challenge. PWD may be used to predict cardiovascular response to orthostatic stress upon head-up tilt in MSA patients. |
| format | Article |
| id | doaj-art-2725c7d1bf50490a9f09f497fa1f6a94 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-2725c7d1bf50490a9f09f497fa1f6a942025-02-03T05:58:58ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/548529548529Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table StudyKe-Vin Chang0Wen-Shiang Chen1Ruey-Meei Wu2Ssu-Yuan Chen3Hsiu-Yu Shen4Ching Lan5Yen-Ho Wang6Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei 10002, TaiwanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei 10002, TaiwanDepartment of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei 10002, TaiwanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei 10002, TaiwanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei 10002, TaiwanDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei 10002, TaiwanThe study aim was to assess sympathetic vasomotor response (SVR) by using pulsed wave Doppler (PWD) ultrasound in patients with multiple system atrophy (MSA) and correlate with the tilt table study. We recruited 18 male patients and 10 healthy men as controls. The SVR of the radial artery was evaluated by PWD, using inspiratory cough as a provocative maneuver. The response to head-up tilt was studied by a tilt table with simultaneous heart rate and blood pressure recording. The hemodynamic variables were compared between groups, and were examined by correlation analysis. Regarding SVR, MSA patients exhibited a prolonged latency and less heart rate acceleration following inspiratory cough. Compared with the tilt table test, the elevation of heart rate upon SVR was positively correlated to the increase of heart rate after head-up tilt. The correlation analysis indicated that the magnitude of blood pressure drop from supine to upright was positively associated with the SVR latency but negatively correlated with the heart rate changes upon SVR. The present study demonstrated that blunted heart rate response might explain MSA's vulnerability to postural challenge. PWD may be used to predict cardiovascular response to orthostatic stress upon head-up tilt in MSA patients.http://dx.doi.org/10.1100/2012/548529 |
| spellingShingle | Ke-Vin Chang Wen-Shiang Chen Ruey-Meei Wu Ssu-Yuan Chen Hsiu-Yu Shen Ching Lan Yen-Ho Wang Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study The Scientific World Journal |
| title | Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study |
| title_full | Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study |
| title_fullStr | Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study |
| title_full_unstemmed | Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study |
| title_short | Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study |
| title_sort | pulsed wave doppler ultrasound is useful to assess vasomotor response in patients with multiple system atrophy and well correlated with tilt table study |
| url | http://dx.doi.org/10.1100/2012/548529 |
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