Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis

Monkeypox is primarily a painful cutaneous disease with occasional systemic manifestations. Monkeypox is transmitted predominantly through close physical contact and occasionally sexual contact. The first case was reported in the United States on May 17, 2022, in a recent monkeypox worldwide outbrea...

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Main Authors: Sobaan Taj, Chris Austin, Azhar Hussain, Maryam Salma Babar, Harshavardhan Sanekommu, Steven Imburgio, Anmol Johal, Alejandro CruzPonce, Apurva Vedire, Edward Liu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2023/9981631
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author Sobaan Taj
Chris Austin
Azhar Hussain
Maryam Salma Babar
Harshavardhan Sanekommu
Steven Imburgio
Anmol Johal
Alejandro CruzPonce
Apurva Vedire
Edward Liu
author_facet Sobaan Taj
Chris Austin
Azhar Hussain
Maryam Salma Babar
Harshavardhan Sanekommu
Steven Imburgio
Anmol Johal
Alejandro CruzPonce
Apurva Vedire
Edward Liu
author_sort Sobaan Taj
collection DOAJ
description Monkeypox is primarily a painful cutaneous disease with occasional systemic manifestations. Monkeypox is transmitted predominantly through close physical contact and occasionally sexual contact. The first case was reported in the United States on May 17, 2022, in a recent monkeypox worldwide outbreak. We present a case of severe gastrointestinal bleeding as an atypical manifestation of monkeypox infection in a 40-year-old male with HIV. In our case, monkeypox-induced proctocolitis progressed to severe rectal bleeding requiring one unit of packed red blood cells transfusion despite one week of tecovirimat (TPOXX) therapy. So, patients should be educated about the possibility of unusual complications of monkeypox infection, i.e., bleeding in immunocompromised hosts.
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-271a0510249a43b0a21b79b7f07052872025-02-03T01:29:29ZengWileyCase Reports in Gastrointestinal Medicine2090-65362023-01-01202310.1155/2023/9981631Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated ProctocolitisSobaan Taj0Chris Austin1Azhar Hussain2Maryam Salma Babar3Harshavardhan Sanekommu4Steven Imburgio5Anmol Johal6Alejandro CruzPonce7Apurva Vedire8Edward Liu9Department of MedicineDepartment of MedicineAmeer ud Din Medical CollegeCleveland ClinicDepartment of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineMonkeypox is primarily a painful cutaneous disease with occasional systemic manifestations. Monkeypox is transmitted predominantly through close physical contact and occasionally sexual contact. The first case was reported in the United States on May 17, 2022, in a recent monkeypox worldwide outbreak. We present a case of severe gastrointestinal bleeding as an atypical manifestation of monkeypox infection in a 40-year-old male with HIV. In our case, monkeypox-induced proctocolitis progressed to severe rectal bleeding requiring one unit of packed red blood cells transfusion despite one week of tecovirimat (TPOXX) therapy. So, patients should be educated about the possibility of unusual complications of monkeypox infection, i.e., bleeding in immunocompromised hosts.http://dx.doi.org/10.1155/2023/9981631
spellingShingle Sobaan Taj
Chris Austin
Azhar Hussain
Maryam Salma Babar
Harshavardhan Sanekommu
Steven Imburgio
Anmol Johal
Alejandro CruzPonce
Apurva Vedire
Edward Liu
Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
Case Reports in Gastrointestinal Medicine
title Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
title_full Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
title_fullStr Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
title_full_unstemmed Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
title_short Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
title_sort severe gastrointestinal hemorrhage due to monkeypox virus associated proctocolitis
url http://dx.doi.org/10.1155/2023/9981631
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