Suppressive Effects of GSS on Lipopolysaccharide-Induced Endothelial Cell Injury and ALI via TNF-α and IL-6

Suppressive Effects of GSS on Lipopolysaccharide-Induced Endothelial Cell Injury and ALI via TNF-α and IL-6

Background. Under septic conditions, LPS induced lung vascular endothelial cell (EC) injury, and the release of inflammatory mediator launches and aggravates acute lung injury (ALI). There are no effective therapeutic options for ALI. Genistein-3′-sodium sulfonate (GSS) is a derivative of native soy...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lei Yi, Zengding Zhou, Yijuan Zheng, Mengling Chang, Xiaoqin Huang, Feng Guo, Quanming Zhao, Jingning Huan
Format:	Article
Language:	English
Published:	Wiley 2019-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2019/4251394
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX2) Mediated TNF-α and IL-6 Production in Macrophages
by: Tao Meng, et al.
Published: (2013-01-01)

Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake
by: Veedamali S. Subramanian, et al.
Published: (2021-01-01)

Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1
by: Yong Li, et al.
Published: (2021-01-01)

Serum IL-1β, IL-6, IL-8, and TNF-α Levels in Early Diagnosis and Management of Neonatal Sepsis
by: A. Nese Citak Kurt, et al.
Published: (2007-01-01)

Effect of Proinflammatory Cytokines (IL-6, TNF-α, and IL-1β) on Clinical Manifestations in Indian SLE Patients
by: Vinod Umare, et al.
Published: (2014-01-01)

Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells
by: Angela P. Bastidas-Coral, et al.
Published: (2016-01-01)

Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy
by: Xu-dong Liu, et al.
Published: (2019-01-01)

Functional resting state connectivity is differentially associated with IL-6 and TNF-α in depression and in healthy controls
by: Christian N. Schmitz, et al.
Published: (2025-01-01)

Expression of H2S in Gestational Diabetes Mellitus and Correlation Analysis with Inflammatory Markers IL-6 and TNF-α
by: Yucui Teng, et al.
Published: (2020-01-01)

Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's disease
by: Cem Evereklioglu, et al.
Published: (2002-01-01)

Correction: Evaluation of TNF-α, IL-10 and IL-6 Cytokine Production and Their Correlation with Genotype Variants amongst Tuberculosis Patients and Their Household Contacts.
by: Lavanya Joshi, et al.
Published: (2025-01-01)

Associations of Trauma Severity with Mean Platelet Volume and Levels of Systemic Inflammatory Markers (IL1β, IL6, TNFα, and CRP)
by: Baris Alper, et al.
Published: (2016-01-01)

Effects of IL-6 and TNF-α Cytokines on Cell Proliferation in Androgen Dependent/Independent Prostate Cancer Cell Lines
by: Serhad Onat, et al.
Published: (2024-03-01)

Low IL-6, IL-10, and TNF-α and High IL-13 Cytokine Levels Are Associated with Severe Hepatic Fibrosis in Schistosoma mansoni Chronically Exposed Individuals
by: Mable M. Mutengo, et al.
Published: (2018-01-01)

IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2
by: Rong Xu, et al.
Published: (2015-01-01)

Levels of Cytokines (IL-1β, IL-2, IL-6, IL-8, TNF-α) and Trace Elements (Zn, Cu) in Breast Milk From Mothers of Preterm and Term Infants
by: Bilal Ustundag, et al.
Published: (2005-01-01)

Notch Signaling Mediates TNF-α-Induced IL-6 Production in Cultured Fibroblast-Like Synoviocytes from Rheumatoid Arthritis
by: Zhijun Jiao, et al.
Published: (2012-01-01)

Anti-IL-6 Receptor Antibody Causes Less Promotion of Tuberculosis Infection than Anti-TNF-𝛼 Antibody in Mice
by: Masaji Okada, et al.
Published: (2011-01-01)

The Expression of IL-6, TNF-α, and MCP-1 in Respiratory Viral Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
by: Jingtong Zheng, et al.
Published: (2017-01-01)

Genetic polymorphism of xenobiotic biotransformation genes, TNF-α and IL-4 in obstructive jaundice
by: A. A. Natalsky, et al.
Published: (2015-09-01)

Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-α, and HMGB1
by: Huizhen Fan, et al.
Published: (2018-01-01)

Anti-TNF-α Therapy Suppresses Proinflammatory Activities of Mucosal Neutrophils in Inflammatory Bowel Disease
by: Cui Zhang, et al.
Published: (2018-01-01)

Direct effects of prolonged TNF-α and IL-6 exposure on neural activity in human iPSC-derived neuron-astrocyte co-cultures
by: Noah Goshi, et al.
Published: (2025-02-01)

Salivary IL-17A, IL-17F, and TNF-α Are Associated with Disease Advancement in Patients with Oral and Oropharyngeal Cancer
by: Kinga Zielińska, et al.
Published: (2020-01-01)

Panduratin A Inhibits TNF Alpha-Stimulated Endothelial Cell Activation Through Suppressing the NF-κB Pathway
by: Kriangkrai Kiatsoonthon, et al.
Published: (2024-12-01)

Does Toxoplasma gondii Infection Affect the Levels of IgE and Cytokines (IL-5, IL-6, IL-10, IL-12, and TNF-alpha)?
by: Joanna Matowicka-Karna, et al.
Published: (2009-01-01)

Modulatory Effect of 1,25-Dihydroxyvitamin D3 on IL1β-Induced RANKL, OPG, TNFα, and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A
by: Xiaoke Feng, et al.
Published: (2013-01-01)

Deviations in Circulating TNFα Levels and TNFα Production by Mononuclear Cells in Healthy Human Populations
by: T. Mózes, et al.
Published: (2011-01-01)

Effect of Lipoxin A4 on Lipopolysaccharide-Induced Endothelial Hyperpermeability
by: Huayan Pang, et al.
Published: (2011-01-01)

Effects of Ginkgo biloba Extract on Inflammatory Mediators (SOD, MDA, TNF-α, NF-κBp65, IL-6) in TNBS-Induced Colitis in Rats
by: Yan-Hong Zhou, et al.
Published: (2006-01-01)

The TNF Receptors p55 and p75 Mediate Chemotaxis of PMN Induced by TNFα and a TNFα 36–62 Peptide
by: Ø. Rekdal, et al.
Published: (1994-01-01)

Nerve Growth Factor Regulation by TNF-α and IL-1β in Synovial Macrophages and Fibroblasts in Osteoarthritic Mice
by: Shotaro Takano, et al.
Published: (2016-01-01)

Expression of lipocortins in human bronchial epithelial cells: effects of IL-1β , TNF-α, LPS and dexamethasone
by: M. M. Verheggen, et al.
Published: (1996-01-01)

Relationship of Serum Levels of IL-17, IL-18, TNF-α, and Lung Function Parameters in Patients with COPD, Asthma-COPD Overlap, and Bronchial Asthma
by: Nailya Kubysheva, et al.
Published: (2020-01-01)

The Effect of TNF-α on CHD and the Relationship between TNF-α Antagonist and CHD in Rheumatoid Arthritis: A Systematic Review
by: Yezhou Qian, et al.
Published: (2022-01-01)

Changes in TNF and IL-6 production after diphtheria toxoid vaccination: drug modulation of the cytokine levels
by: A. L. Pukhalsky, et al.
Published: (1996-01-01)

The Role of IL-6 and TNF-Alpha Biomarkers in Predicting Disability Outcomes in Acute Ischemic Stroke Patients
by: Ciprian-Ionuț Băcilă, et al.
Published: (2025-01-01)

Human Mast Cells (HMC-1 5C6) Enhance Interleukin-6 Production by Quiescent and Lipopolysaccharide-Stimulated Human Coronary Artery Endothelial Cells
by: Damandeep S. Walia, et al.
Published: (2012-01-01)

Serum Levels of TNF-α, IL-12/23 p40, and IL-17 in Psoriatic Patients with and without Nail Psoriasis: A Cross-Sectional Study
by: Aikaterini Kyriakou, et al.
Published: (2014-01-01)

Elevated Circulating IL-1β and TNF-Alpha, and Unaltered IL-6 in First-Trimester Pregnancies Complicated by Threatened Abortion With an Adverse Outcome
by: Nicolaos Vitoratos, et al.
Published: (2006-01-01)