Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy
We present a case of an 18-month-old boy who showed severe clinical signs indicative of acute hemorrhagic edema of infancy (AHEI) with painful purpuric skin affection primarily of the face and marked edema of the ears. The histological findings were diagnostic for leukocytoclastic vasculitis and thu...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/853038 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832548663291805696 |
|---|---|
| author | Jeyanthini Risikesan Uffe Koppelhus Torben Steiniche Mette Deleuran Troels Herlin |
| author_facet | Jeyanthini Risikesan Uffe Koppelhus Torben Steiniche Mette Deleuran Troels Herlin |
| author_sort | Jeyanthini Risikesan |
| collection | DOAJ |
| description | We present a case of an 18-month-old boy who showed severe clinical signs indicative of acute hemorrhagic edema of infancy (AHEI) with painful purpuric skin affection primarily of the face and marked edema of the ears. The histological findings were diagnostic for leukocytoclastic vasculitis and thus met the histological criteria for AHEI. Indicative of infection as causative agent for the condition were symptoms of gastroenteritis. High-dose intravenous corticosteroids led to a fast resolution of symptoms and normalization of laboratory parameters. AHEI is usually not described as being very responsive to corticosteroids. The case presented here indicates that severe cases of AHEI can be treated with high-dose intravenous corticosteroids resulting in significant relief and shortening of the symptoms. Clinical followup showed no underlying malignancy or other severe chronic systemic diseases thus confirming earlier reports that AHEI is not associated with such conditions. The differential diagnoses with AHEI are discussed. |
| format | Article |
| id | doaj-art-270a485b5102471082839d1692cc07f0 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-270a485b5102471082839d1692cc07f02025-02-03T06:13:17ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712014-01-01201410.1155/2014/853038853038Methylprednisolone Therapy in Acute Hemorrhagic Edema of InfancyJeyanthini Risikesan0Uffe Koppelhus1Torben Steiniche2Mette Deleuran3Troels Herlin4Department of Pediatrics, Aarhus University Hospital, 8200 Aarhus N, DenmarkDepartment of Dermatology, Aarhus University Hospital, Aarhus C, 8000 Aarhus, DenmarkDepartment of Pathology, Aarhus University Hospital, Aarhus C, 8000 Aarhus, DenmarkDepartment of Dermatology, Aarhus University Hospital, Aarhus C, 8000 Aarhus, DenmarkDepartment of Pediatrics, Aarhus University Hospital, 8200 Aarhus N, DenmarkWe present a case of an 18-month-old boy who showed severe clinical signs indicative of acute hemorrhagic edema of infancy (AHEI) with painful purpuric skin affection primarily of the face and marked edema of the ears. The histological findings were diagnostic for leukocytoclastic vasculitis and thus met the histological criteria for AHEI. Indicative of infection as causative agent for the condition were symptoms of gastroenteritis. High-dose intravenous corticosteroids led to a fast resolution of symptoms and normalization of laboratory parameters. AHEI is usually not described as being very responsive to corticosteroids. The case presented here indicates that severe cases of AHEI can be treated with high-dose intravenous corticosteroids resulting in significant relief and shortening of the symptoms. Clinical followup showed no underlying malignancy or other severe chronic systemic diseases thus confirming earlier reports that AHEI is not associated with such conditions. The differential diagnoses with AHEI are discussed.http://dx.doi.org/10.1155/2014/853038 |
| spellingShingle | Jeyanthini Risikesan Uffe Koppelhus Torben Steiniche Mette Deleuran Troels Herlin Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy Case Reports in Dermatological Medicine |
| title | Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy |
| title_full | Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy |
| title_fullStr | Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy |
| title_full_unstemmed | Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy |
| title_short | Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy |
| title_sort | methylprednisolone therapy in acute hemorrhagic edema of infancy |
| url | http://dx.doi.org/10.1155/2014/853038 |
| work_keys_str_mv | AT jeyanthinirisikesan methylprednisolonetherapyinacutehemorrhagicedemaofinfancy AT uffekoppelhus methylprednisolonetherapyinacutehemorrhagicedemaofinfancy AT torbensteiniche methylprednisolonetherapyinacutehemorrhagicedemaofinfancy AT mettedeleuran methylprednisolonetherapyinacutehemorrhagicedemaofinfancy AT troelsherlin methylprednisolonetherapyinacutehemorrhagicedemaofinfancy |