Routes to Multiple Equilibria for Mass-Action Kinetic Systems

In this work we explore two potential mechanisms inducing multiple equilibria for weakly reversible networks with mass-action kinetics. The study is performed on a class of polynomial dynamic systems that, under some mild assumptions, are able to accommodate in their state-space form weakly reversib...

Full description

Saved in:
Bibliographic Details
Main Authors: Antonio A. Alonso, Irene Otero-Muras, Manuel Pájaro
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2018/3912627
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this work we explore two potential mechanisms inducing multiple equilibria for weakly reversible networks with mass-action kinetics. The study is performed on a class of polynomial dynamic systems that, under some mild assumptions, are able to accommodate in their state-space form weakly reversible mass-action kinetic networks. The contribution is twofold. We provide an explicit representation of the set of all positive equilibria attained by the system class in terms of a set of (positive parameter dependent) algebraic relations. With this in hand, we prove that deficiency-one networks can only admit multiple equilibria via folding of the equilibrium manifold, whereas a bifurcation leading to multiple branches is only possible in networks with deficiencies larger than one. Interestingly, some kinetic networks within this latter class are capable of sustaining multiple equilibria for any reaction simplex, as we illustrate with one example.
ISSN:1076-2787
1099-0526