Immunomodulatory role of phagocyte-derived chloramines involving lymphocyte glutathione

This study shows that human lymphocytes markedly decrease chloramines (long-lived oxidants) generated by polymorphonuclear neutrophils (PMN) after stimulation by phorbol-myristate-acetate or opsonized zymosan. In a cell-free model, reduced glutathione (GSH) scavenged chloramines, giving rise to oxid...

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Bibliographic Details
Main Authors: Véronique Witko-Sarsat, Anh Thu Nguyen, Béatrice Descamps-Latscha
Format: Article
Language:English
Published: Wiley 1993-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935193000328
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