Uncovering the Link Between Kynurenic Acid Pathway and Kidney Failure

Uncovering the Link Between Kynurenic Acid Pathway and Kidney Failure

Introduction: Recent studies have focused on some uremic toxins, particularly those derived from tryptophan, as potential modifiable risk factors of chronic kidney disease (CKD) progression. The kynurenine pathway is the major enzymatic pathway for sequentially catabolizing tryptophan, resulting in...

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Main Authors: Carolla El Chamieh, Sophie Liabeuf, Islam Amine Larabi, Natalia Alencar De Pinho, Margaux Costes-Albrespic, Luc Frimat, Céline Lange, Yves-Édouard Herpe, Jean-Charles Martin, Pierre Letourneau, Benoit Bérengère, Christophe Soulage, Stéphane Burtey, Jean-Claude Alvarez, Laetitia Koppe, Ziad A. Massy, Prs T. Hannedouche, B. Moulin, Dr A. Klein, Pr C. Combe, Dr J.P. Bourdenx, Dr A. Keller, Dr C. Delclaux, Dr B. Vendrely, Dr B. Deroure, Dr A. Lacraz, Dr T. Lobbedez, Dr I. Landru, Pr Z. Massy, Pr P. Lang, Dr X. Belenfant, Pr E. Thervet, Dr P. Urena, Dr M. Delahousse, Dr C. Vela, Pr M. Essig, Dr D. Clément, Dr H. Sekhri, Dr M. Smati, Dr M. Jamali, Dr B. Hacq, Dr V. Panescu, Dr M. Bellou, Pr Luc Frimat, Pr N. Kamar, Prs C. Noël et F. Glowacki, Dr N. Maisonneuve, Dr R. Azar, Dr M. Hoffmann, Pr M. Hourmant, Dr A. Testa, Dr D. Besnier, Pr G. Choukroun, Dr G. Lambrey, Pr S. Burtey, Dr G. Lebrun, Dr E. Magnant, Pr M. Laville, Pr D. Fouque, L. Juillard, Dr C. Chazot, Pr P. Zaoui, Dr F. Kuentz
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Kidney International Reports
Subjects:
chronic kidney disease
kidney failure
kynurenic acid pathway
kynurenine
tryptophan
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925001147
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