The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients
Thalassaemia and other haemoglobinopathies constitute an important health problem in Mediterranean countries, placing a tremendous emotional, psychological, and economic burden on their National Health systems. The development of new chelators in the most recent years had a major impact on the treat...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Anemia |
| Online Access: | http://dx.doi.org/10.1155/2011/435683 |
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| author | Adriana Ceci Laura Mangiarini Mariagrazia Felisi Franco Bartoloni Angela Ciancio Marcello Capra Domenico D'Ascola Paolo Cianciulli Aldo Filosa |
| author_facet | Adriana Ceci Laura Mangiarini Mariagrazia Felisi Franco Bartoloni Angela Ciancio Marcello Capra Domenico D'Ascola Paolo Cianciulli Aldo Filosa |
| author_sort | Adriana Ceci |
| collection | DOAJ |
| description | Thalassaemia and other haemoglobinopathies constitute an important health problem in Mediterranean countries, placing a tremendous emotional, psychological, and economic burden on their National Health systems. The development of new chelators in the most recent years had a major impact on the treatment of thalassaemia and on the quality of life of thalassaemic patients. A new initiative was promoted by the Italian Ministry of Health, establishing a Registry for thalassaemic patients to serve as a tool for the development of cost-effective diagnostic and therapeutic approaches and for the definition of guidelines supporting the most appropriate management of the iron-chelating therapy and a correct use of the available iron-chelating agents. This study represents the analysis of the preliminary data collected for the evaluation of current status of the iron chelation practice in the Italian thalassaemic population and describes how therapeutic interventions can widely differ in the different patients' age groups. |
| format | Article |
| id | doaj-art-26c3f01f44294adbb631f13ef0e2f893 |
| institution | Kabale University |
| issn | 2090-1267 2090-1275 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Anemia |
| spelling | doaj-art-26c3f01f44294adbb631f13ef0e2f8932025-02-03T05:57:07ZengWileyAnemia2090-12672090-12752011-01-01201110.1155/2011/435683435683The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic PatientsAdriana Ceci0Laura Mangiarini1Mariagrazia Felisi2Franco Bartoloni3Angela Ciancio4Marcello Capra5Domenico D'Ascola6Paolo Cianciulli7Aldo Filosa8Consorzio per Valutazioni Biologiche e Farmacologiche, Via L. Porta 14, 27100 Pavia, ItalyConsorzio per Valutazioni Biologiche e Farmacologiche, Via L. Porta 14, 27100 Pavia, ItalyConsorzio per Valutazioni Biologiche e Farmacologiche, Via L. Porta 14, 27100 Pavia, ItalyI.RI.D.I.A. srl, Viale Concilio Vaticano II 75/B, 70124 Bari, ItalyU.S. Dipartimentale Ematologia-DH Talassemia, Ospedale “Madonna delle Grazie”, Via Montescagliaso C. da Cattedra Ambulante 1, 75100 Matera, ItalyUOC Ematologia-Emoglobinopatie, Ospedale “G. Di Cristina”, Via Benedettini 1, 90100 Palermo, ItalyCentro Microcitemia, Azienda Ospedaliera “Bianchi Melacrino Morelli”, Via Melacrino 1, 89126 Reggio Calabria, ItalyU.O. Day Hospital Talassemia, Ospedale “S. Eugenio”, Piazzale Umanesimo 10, 00144 Roma, ItalyUOS Talassemia Pediatrica ed Emoglobinopatie Pediatriche, Azienda Ospedaliera di Rilievo Nazionale “Antonio Cardarelli”, Via A. Cardarelli 9, 80131 Napoli, ItalyThalassaemia and other haemoglobinopathies constitute an important health problem in Mediterranean countries, placing a tremendous emotional, psychological, and economic burden on their National Health systems. The development of new chelators in the most recent years had a major impact on the treatment of thalassaemia and on the quality of life of thalassaemic patients. A new initiative was promoted by the Italian Ministry of Health, establishing a Registry for thalassaemic patients to serve as a tool for the development of cost-effective diagnostic and therapeutic approaches and for the definition of guidelines supporting the most appropriate management of the iron-chelating therapy and a correct use of the available iron-chelating agents. This study represents the analysis of the preliminary data collected for the evaluation of current status of the iron chelation practice in the Italian thalassaemic population and describes how therapeutic interventions can widely differ in the different patients' age groups.http://dx.doi.org/10.1155/2011/435683 |
| spellingShingle | Adriana Ceci Laura Mangiarini Mariagrazia Felisi Franco Bartoloni Angela Ciancio Marcello Capra Domenico D'Ascola Paolo Cianciulli Aldo Filosa The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients Anemia |
| title | The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients |
| title_full | The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients |
| title_fullStr | The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients |
| title_full_unstemmed | The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients |
| title_short | The Management of Iron Chelation Therapy: Preliminary Data from a National Registry of Thalassaemic Patients |
| title_sort | management of iron chelation therapy preliminary data from a national registry of thalassaemic patients |
| url | http://dx.doi.org/10.1155/2011/435683 |
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