Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus

Cerebral aneurysms secondary to human immunodeficiency virus vasculopathy are a diagnosis by exclusion and its mechanism is unknown. We report on a 21-year-old male with human immunodeficiency virus infection and suboptimal virological control, despite highly active antiretroviral therapy. An incide...

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Main Authors: Talia Unice, Poobalan Naidoo, Pranav Hiralal, Yeshkhir Naidoo, Somasundram Pillay
Format: Article
Language:English
Published: SAGE Publishing 2023-11-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X231211048
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author Talia Unice
Poobalan Naidoo
Pranav Hiralal
Yeshkhir Naidoo
Somasundram Pillay
author_facet Talia Unice
Poobalan Naidoo
Pranav Hiralal
Yeshkhir Naidoo
Somasundram Pillay
author_sort Talia Unice
collection DOAJ
description Cerebral aneurysms secondary to human immunodeficiency virus vasculopathy are a diagnosis by exclusion and its mechanism is unknown. We report on a 21-year-old male with human immunodeficiency virus infection and suboptimal virological control, despite highly active antiretroviral therapy. An incidental discovery of multiple cerebral aneurysms occurred in this patient, who initially presented with signs of disorientation, acute psychosis, and a history of blunt cranial trauma. A non-contrasted computerized tomography scan of the encephalon showed no intracranial hemorrhage but multiple cerebral (saccular and fusiform) aneurysms. Subsequently, a non-urgent computerized tomography angiogram of the cerebral vasculature corroborated the existence of multiple cerebral aneurysms. Despite investigation, no secondary etiological factors for the aneurysmal condition were identified. The multitude of cerebral aneurysms was consequently ascribed to human immunodeficiency virus-associated vasculopathy. The patient was managed conservatively. At discharge, he was lucid and apsychotic. A unique aspect of the case is the presence of both fusiform and saccular cerebral aneurysms.
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institution Kabale University
issn 2050-313X
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publisher SAGE Publishing
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series SAGE Open Medical Case Reports
spelling doaj-art-26aad0e33ecd469abca9ec16095bab862025-01-29T13:04:31ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2023-11-011110.1177/2050313X231211048Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency VirusTalia UnicePoobalan NaidooPranav HiralalYeshkhir NaidooSomasundram PillayCerebral aneurysms secondary to human immunodeficiency virus vasculopathy are a diagnosis by exclusion and its mechanism is unknown. We report on a 21-year-old male with human immunodeficiency virus infection and suboptimal virological control, despite highly active antiretroviral therapy. An incidental discovery of multiple cerebral aneurysms occurred in this patient, who initially presented with signs of disorientation, acute psychosis, and a history of blunt cranial trauma. A non-contrasted computerized tomography scan of the encephalon showed no intracranial hemorrhage but multiple cerebral (saccular and fusiform) aneurysms. Subsequently, a non-urgent computerized tomography angiogram of the cerebral vasculature corroborated the existence of multiple cerebral aneurysms. Despite investigation, no secondary etiological factors for the aneurysmal condition were identified. The multitude of cerebral aneurysms was consequently ascribed to human immunodeficiency virus-associated vasculopathy. The patient was managed conservatively. At discharge, he was lucid and apsychotic. A unique aspect of the case is the presence of both fusiform and saccular cerebral aneurysms.https://doi.org/10.1177/2050313X231211048
spellingShingle Talia Unice
Poobalan Naidoo
Pranav Hiralal
Yeshkhir Naidoo
Somasundram Pillay
Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus
SAGE Open Medical Case Reports
title Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus
title_full Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus
title_fullStr Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus
title_full_unstemmed Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus
title_short Multiple fusiform and saccular aneurysms in a person living with Human Immunodeficiency Virus
title_sort multiple fusiform and saccular aneurysms in a person living with human immunodeficiency virus
url https://doi.org/10.1177/2050313X231211048
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AT poobalannaidoo multiplefusiformandsaccularaneurysmsinapersonlivingwithhumanimmunodeficiencyvirus
AT pranavhiralal multiplefusiformandsaccularaneurysmsinapersonlivingwithhumanimmunodeficiencyvirus
AT yeshkhirnaidoo multiplefusiformandsaccularaneurysmsinapersonlivingwithhumanimmunodeficiencyvirus
AT somasundrampillay multiplefusiformandsaccularaneurysmsinapersonlivingwithhumanimmunodeficiencyvirus