G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth
Endometrial carcinoma is the most common cancer of the female reproductive tract. GPER/GPR30 is a 7-transmembrane spanning G protein-coupled receptor that has been identified as the third estrogen receptor, in addition to ERα and ERβ. High GPER expression is predictive of poor survival in endometria...
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Main Authors: | Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Obstetrics and Gynecology International |
Online Access: | http://dx.doi.org/10.1155/2013/472720 |
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