Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG
Purpose of the research: The purpose of this study is to present current knowledge on the use of sodium butyrate in the treatment of irritable bowel syndrome (IBS), with a particular focus on its effects on the microbiota and intestinal barrier. Material and Methods: The study is based on a revi...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-04-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/59419 |
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| _version_ | 1849761104271507456 |
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| author | Karolina Grabowska Martyna Grabowska Aleksandra Wiśniewska Jakub Dąbek Wiktoria Kosucka Dominik Balik Joanna Lara Anna Kwaśniewska Karolina Kaszyńska Jagoda Kubicka |
| author_facet | Karolina Grabowska Martyna Grabowska Aleksandra Wiśniewska Jakub Dąbek Wiktoria Kosucka Dominik Balik Joanna Lara Anna Kwaśniewska Karolina Kaszyńska Jagoda Kubicka |
| author_sort | Karolina Grabowska |
| collection | DOAJ |
| description |
Purpose of the research:
The purpose of this study is to present current knowledge on the use of sodium butyrate in the treatment of irritable bowel syndrome (IBS), with a particular focus on its effects on the microbiota and intestinal barrier.
Material and Methods:
The study is based on a review of the scientific literature, including clinical and experimental studies on the effects of sodium butyrate on the gastrointestinal tract.
Results:
Sodium butyrate strengthens the intestinal barrier, exhibits anti-inflammatory effects and influences the microbiota. Clinical studies confirm that its supplementation reduces abdominal pain, improves bowel rhythm and reduces bloating in IBS patients, resulting in a better quality of life.
Conclusions:
Sodium butyrate has the potential to be an effective support for IBS therapy, but further research is needed to determine its long-term safety and optimal dosage. In addition, changes in faecal levels of short-chain fatty acids (SCFAs) may act as a potential biomarker for IBS, but extra studies are needed to confirm their diagnostic value and define accurate reference levels.
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| format | Article |
| id | doaj-art-265a5213182c48038a37de81942b5ce9 |
| institution | DOAJ |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-265a5213182c48038a37de81942b5ce92025-08-20T03:06:09ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-04-014010.12775/QS.2025.40.59419Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KGKarolina Grabowska0https://orcid.org/0009-0006-7877-2512Martyna Grabowskahttps://orcid.org/0009-0002-4030-8272Aleksandra Wiśniewskahttps://orcid.org/0009-0008-4393-0829Jakub Dąbekhttps://orcid.org/0009-0006-1367-7629Wiktoria Kosuckahttps://orcid.org/0009-0001-1101-7364Dominik Balikhttps://orcid.org/0009-0003-9921-3056Joanna Larahttps://orcid.org/0009-0000-9411-4815Anna Kwaśniewskahttps://orcid.org/0009-0006-1080-1276Karolina Kaszyńskahttps://orcid.org/0009-0000-6453-1159Jagoda Kubickahttps://orcid.org/0009-0004-6464-4777Faculty of Medicine, Medical Univeristy of Lodz Purpose of the research: The purpose of this study is to present current knowledge on the use of sodium butyrate in the treatment of irritable bowel syndrome (IBS), with a particular focus on its effects on the microbiota and intestinal barrier. Material and Methods: The study is based on a review of the scientific literature, including clinical and experimental studies on the effects of sodium butyrate on the gastrointestinal tract. Results: Sodium butyrate strengthens the intestinal barrier, exhibits anti-inflammatory effects and influences the microbiota. Clinical studies confirm that its supplementation reduces abdominal pain, improves bowel rhythm and reduces bloating in IBS patients, resulting in a better quality of life. Conclusions: Sodium butyrate has the potential to be an effective support for IBS therapy, but further research is needed to determine its long-term safety and optimal dosage. In addition, changes in faecal levels of short-chain fatty acids (SCFAs) may act as a potential biomarker for IBS, but extra studies are needed to confirm their diagnostic value and define accurate reference levels. https://apcz.umk.pl/QS/article/view/59419sodium butyrateirritable bowel syndromebutyric acidSCFAs |
| spellingShingle | Karolina Grabowska Martyna Grabowska Aleksandra Wiśniewska Jakub Dąbek Wiktoria Kosucka Dominik Balik Joanna Lara Anna Kwaśniewska Karolina Kaszyńska Jagoda Kubicka Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG Quality in Sport sodium butyrate irritable bowel syndrome butyric acid SCFAs |
| title | Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG |
| title_full | Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG |
| title_fullStr | Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG |
| title_full_unstemmed | Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG |
| title_short | Sodium Butyrate in The Treatment of Irritable Bowel Syndrome KG |
| title_sort | sodium butyrate in the treatment of irritable bowel syndrome kg |
| topic | sodium butyrate irritable bowel syndrome butyric acid SCFAs |
| url | https://apcz.umk.pl/QS/article/view/59419 |
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